NeoGenesis: S2RM Stem Cell Released Molecules, Authorized in the US
Shop the complete NeoGenesis range at US retail price: Recovery, Booster, Skin Serum and Eye Serum built on patented S2RM technology, Skin Restore and Vibrant C targeted serums, Salicylic and Mandelic acids, Enzyme and Fresh Face masks, Barrier Renewal Cream, Intensive and Light Moisturizers, MB-1 and MB-2 probiotics, Body Cream, Moisturizing Mist, and the S3RM Hair Thickening, NeoBrow and NeoLash serums. SkinCrew is an Authorized NeoGenesis US Retailer, so every bottle is sourced direct from the brand, fresh and authentic, with fast US shipping.
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NeoGenesis Hair Thickening Serum
NeoGenesis Hair Thickening Serum
- Regular price
- $249.00
- Sale price
- $249.00
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NeoGenesis Body Cream
NeoGenesis Body Cream
- Regular price
- From $15.00
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- From $15.00
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NeoGenesis Moisturizing Mist
NeoGenesis Moisturizing Mist
- Regular price
- From $20.00
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- From $20.00
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NeoGenesis Barrier Renewal Cream
NeoGenesis Barrier Renewal Cream
- Regular price
- From $25.00
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- From $25.00
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NeoGenesis Light Moisturizer
NeoGenesis Light Moisturizer
- Regular price
- From $20.00
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- From $20.00
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NeoGenesis Intensive Moisturizer
NeoGenesis Intensive Moisturizer
- Regular price
- From $20.00
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- From $20.00
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NeoGenesis Fresh Face Rejuvenating Peat Mask
NeoGenesis Fresh Face Rejuvenating Peat Mask
- Regular price
- From $23.00
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- From $23.00
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NeoGenesis Enzyme Cream Mask
NeoGenesis Enzyme Cream Mask
- Regular price
- From $23.00
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- From $23.00
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NeoGenesis Mandelic Acid 8%
NeoGenesis Mandelic Acid 8%
- Regular price
- From $13.00
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- From $13.00
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NeoGenesis Salicylic Acid Gel
NeoGenesis Salicylic Acid Gel
- Regular price
- From $46.00
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- From $46.00
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NeoGenesis Vibrant C Serum
NeoGenesis Vibrant C Serum
- Regular price
- From $31.50
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- From $31.50
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NeoGenesis Skin Restore Serum
NeoGenesis Skin Restore Serum
- Regular price
- From $29.00
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- From $29.00
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NeoGenesis Skin Serum
NeoGenesis Skin Serum
- Regular price
- From $37.50
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- From $37.50
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NeoGenesis Eye Serum
NeoGenesis Eye Serum
- Regular price
- From $39.50
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- From $39.50
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NeoGenesis Booster
NeoGenesis Booster
- Regular price
- From $57.50
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- From $57.50
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NeoGenesis Recovery
NeoGenesis Recovery
- Regular price
- From $69.00
- Sale price
- From $69.00
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NeoGenesis Erase The Day
NeoGenesis Erase The Day
- Regular price
- $56.00
- Sale price
- $56.00
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NeoGenesis Cleanser
NeoGenesis Cleanser
- Regular price
- From $20.00
- Sale price
- From $20.00
- Regular price
NeoGenesis: S2RM Stem Cell Released Molecules, Authorized in the US
NeoGenesis is a US skincare brand built on patented S2RM technology: stem cell released molecules, the complete secretome of human fibroblast and adipose mesenchymal stem cells. Rather than isolating one growth factor or one exosome fraction, NeoGenesis delivers the whole molecular profile these cells release, growth factors, peptides, cytokines, antioxidants and extracellular vesicles, in concentrations from 1% to 70%. The products contain conditioned media, never live cells. Around the serums sit targeted treatments (HPR vitamin A, liposomal vitamin C, salicylic and mandelic acids, enzyme and peat masks), barrier moisturizers, live probiotic products and S3RM serums for hair, brows and lashes.
NeoGenesis sells through licensed skincare professionals and authorized retailers, never open marketplaces. SkinCrew is an Authorized NeoGenesis US Retailer, so every Recovery, Booster, Skin Serum, Barrier Renewal Cream and NeoLash is sourced direct from the brand, fresh and authentic, at US retail price with fast shipping. Below: the science, the bestsellers, the full range, a concern guide, before and after cases from NeoGenesis professional partners, and the answers shoppers ask for most.
Patented S2RM Technology
Stem cell released molecules from two cell sources, fibroblast and adipose mesenchymal stem cells, delivered as the complete secretome rather than a single isolated active.
Dermatologist Recommended
NeoGenesis names dermatologist Dr. Raja Sivamani as Head of its Scientific Medical Advisory Board and publishes research on the secretome on its product pages.
Short, Skin-Native Formulas
Fragrance free, pH adjusted to the skin and made for all skin types, with humectants, lipids and natural moisturizing factors the skin already uses.
Authorized & Authentic
SkinCrew is an Authorized NeoGenesis US Retailer. Direct supply from NeoGenesis: never grey-market, expired or diverted stock.
The Science Behind NeoGenesis
NeoGenesis builds its line around the molecules cells release rather than the cells themselves, then surrounds that core with barrier lipids, live probiotics, gentle vitamin A, liposomal vitamin C and hydrating acids. Here is what each platform does and which products use it.
S2RM Technology
Stem cell released molecules: the fresh secretome, including exosomes, ectosomes and the soluble fraction, from human fibroblast and adipose mesenchymal stem cells. The brand describes it as the complete molecular profile skin uses to communicate. In Recovery (70%), Booster (40%), Skin Serum (20%), Eye Serum (10%) and the moisturizers (5%).
S3RM Technology
The hair, brow and lash version adds the secretome of human dermal papilla progenitor cells to the fibroblast and adipose sources, at 60%. Prostaglandin-free and hormone-free. In Hair Thickening Serum, NeoBrow and NeoLash.
Triple Lipid Technology
Three skin-identical ceramides (NP, AP, EOP) with cholesterol and free fatty acids, mimicking the skin’s own lipid structure to limit water loss, delivered with safflower oleosomes and Natural Moisturizing Factors. The core of Barrier Renewal Cream, which NeoGenesis calls the only blemish-safe moisturizer with this technology.
Live Probiotic Bacteria
Live strains, not lysates: MB-1 mist carries live bacteria in a three-ingredient formula, and MB-2 balm suspends five strains (Bacillus coagulans, Bacillus subtilis, Lactobacillus plantarum, Lactococcus lactis, Lactobacillus crispatus) in castor and sunflower oils to support a balanced skin microbiome.
HPR Vitamin A
Skin Restore Serum uses hydroxypinacolone retinoate, a form of vitamin A that works without the conversion steps that make retinol irritating, paired with carotenoids, for smoother, brighter, clearer-looking skin.
Liposomal Vitamin C
Vibrant C Serum delivers three forms of vitamin C in liposomes alongside a wider antioxidant network, for brighter, more even-looking skin and daily defense against free radical damage.
Hydrating Acids & Enzymes
Salicylic Acid Gel (2%) and Mandelic Acid 8% put the acid in a sodium PCA and glycerin base so exfoliation does not mean stripping. Enzyme Cream Mask uses pineapple bromelain and fig ficin with clay; Fresh Face uses peat and fruit extracts.
Natural Moisturizing Factors
Sodium PCA, urea, glycerin, panthenol and two weights of hyaluronic acid, including sodium hyaluronate butyrate, run through Booster, the moisturizers, Body Cream and Moisturizing Mist to replenish water the way skin does it itself.
Descriptions reflect NeoGenesis published product information and research titles. NeoGenesis products are cosmetics, and individual results vary.
NeoGenesis Bestsellers
The NeoGenesis products SkinCrew clients and skincare professionals reach for first, at US retail price. Tap any product to shop.
Shop the Full NeoGenesis Range
All 22 NeoGenesis products at SkinCrew by category. Prices are US retail for the lowest-priced full size; 5 mL and 15 g trial sizes are available on most products from $13.
S2RM Serums
Targeted Treatments
Moisturizers & Barrier
Cleanse, Mist & Balance
Which NeoGenesis Products Are Right for You?
New to NeoGenesis? Start with your primary concern: these are the products our clinical team reaches for first.
How NeoGenesis Compares
Where NeoGenesis sits against single growth factor serums, exosome-only serums and conventional peptide or hyaluronic acid skincare. Each has its place: the right fit depends on your skin and goals.
| Feature | NeoGenesis | Single Growth Factor Serums | Exosome-Only Serums | Peptide / HA Skincare |
|---|---|---|---|---|
| Active approach | Complete secretome (S2RM): growth factors, peptides, cytokines, antioxidants and exosomes together | One growth factor, often recombinant | Isolated exosome fraction | Peptides or hyaluronic acid, no cell-derived molecules |
| Cell sources | Human fibroblast and adipose mesenchymal stem cells; dermal papilla cells added for hair | Not applicable | Varies: plant, animal or human | Not applicable |
| Concentration range | 1% to 70% S2RM, disclosed on every product | Rarely disclosed | Often undisclosed | Not applicable |
| Beyond serums | Moisturizers, barrier cream, acids, masks, live probiotics, body, hair, brow and lash | Usually one serum | Usually one serum | Broad ranges |
| Where it’s sold | Licensed professionals and authorized retailers only | Varies | Varies, often direct online | General retail |
Typical characteristics of each category, not specific competitor products. NeoGenesis products are cosmetics, not drugs, and not a substitute for professional care.
Before & After From NeoGenesis Professional Partners
NeoGenesis publishes unretouched before and after photos submitted by the skincare professionals who use the line. Four examples are below; each product page carries the cases that used that product, with every product in the routine listed.

Dark spots and uneven tone. Products used: Recovery.
Photos courtesy of NeoGenesis. Individual results vary.I tried so many products before yours, nothing worked.Shared by NeoGenesis

Dark spots and uneven tone. Products used: Skin Serum, Intensive Moisturizer.
Photos courtesy of Pamela Vendetti, Pamela V Skincare. Individual results vary.
Thinning hair. Products used: Hair Thickening Serum.
Photos courtesy of Dr. Michael Ryan, Dubai Hair Doctor. Individual results vary.
Post-procedure skin. Products used: Recovery, Moisturizing Mist, Glide Gel, Eye Serum and more.
Photos courtesy of NeoGenesis. Individual results vary.I incorporated NeoGenesis products alongside microcurrent therapy, and the results have been nothing short of extraordinary.Shared by NeoGenesis
Photos courtesy of NeoGenesis professional partners, supplied by the brand. Individual results vary.
NeoGenesis: Frequently Asked Questions
What is NeoGenesis skincare?
NeoGenesis is a US skincare brand built on S2RM, stem cell released molecules: the complete secretome of human fibroblast and adipose mesenchymal stem cells, including growth factors, peptides, cytokines, antioxidants and exosomes. The products contain the conditioned media the cells release, never live cells. The line runs from the 70% S2RM Recovery serum to moisturizers, acids, probiotic products and S3RM hair, brow and lash serums.
What does S2RM mean?
S2RM stands for stem cell released molecules. NeoGenesis describes it as the fresh secretome from human fibroblast and adipose mesenchymal stem cells, which includes exosomes, ectosomes and the soluble fraction of molecules the cells naturally release. Concentrations run from 1% in Moisturizing Mist to 70% in Recovery.
Which NeoGenesis serum should I start with?
Recovery (70% S2RM) is the foundation NeoGenesis recommends when skin needs the most support: visible aging, redness, congestion or post-procedure stress. Booster (40%) adds bioavailable hyaluronic acid for hydration and firmness. Skin Serum (20%) is the daily maintenance serum and the practical choice for body skin. Eye Serum (10%) is for the eye and lip area.
Where can I buy NeoGenesis in the US?
NeoGenesis sells through licensed skincare professionals and authorized retailers. SkinCrew is an Authorized NeoGenesis US Retailer and sources every unit directly from NeoGenesis, so you receive fresh, authentic product covered by the brand guarantee, with fast US shipping.
Is NeoGenesis the same as an exosome serum?
Exosomes are part of it. NeoGenesis S2RM is the complete secretome, so it includes exosomes alongside the other extracellular vesicles, growth factors, peptides, cytokines and antioxidants the cells release. The brand positions this whole-profile approach as different from products built on a single isolated growth factor or exosome fraction.
Can I use NeoGenesis after professional treatments?
NeoGenesis positions Recovery, Barrier Renewal Cream, Moisturizing Mist and MB-2 for skin that is stressed or compromised during and after professional treatments, and its before and after library includes cases from microneedling, chemical peel and laser practices. Follow the guidance of the professional who performed your treatment.
What is the difference between Recovery, Booster and Skin Serum?
All three are S2RM serums. Recovery is 70% S2RM in a minimal base, the highest potency. Booster is 40% S2RM with sodium hyaluronate butyrate for hydration and firmness. Skin Serum is 20% S2RM in a lightweight humectant base for daily use on the face and larger areas. Many routines layer Recovery first, then a second serum, then moisturizer.
Is NeoGenesis good for sensitive skin?
NeoGenesis formulates the line for all skin types and recommends several products specifically for sensitive and reactive skin: Recovery, Skin Serum, Barrier Renewal Cream, Moisturizing Mist, Enzyme Cream Mask and Mandelic Acid 8%. Formulas are fragrance free and pH adjusted to the skin. Introduce one new product at a time.
Does NeoGenesis make hair, brow and lash serums?
Yes. Hair Thickening Serum, NeoBrow and NeoLash use 60% S3RM, which adds the secretome of dermal papilla progenitor cells to the fibroblast and adipose sources in the skin line. All three are prostaglandin-free and hormone-free and are applied twice daily for the first 30 days, then daily.
How much does NeoGenesis cost?
Full sizes run from $20 for Moisturizing Mist 30 mL to $342.50 for Recovery 30 mL, with most serums between $66 and $265. Trial sizes start at $13. SkinCrew sells at NeoGenesis US retail pricing, so a listing far below these prices is a sign of an unauthorized seller.
This guide is maintained by the SkinCrew Clinical Team under medical direction. As an Authorized NeoGenesis US Retailer we source directly from the brand and handle these formulas daily, from storage and freshness to matching products to real concerns. It reflects NeoGenesis published guidance and is educational, not personalized medical advice.
Explore Concerns & Ingredients NeoGenesis Targets
The concern, ingredient, category and brand hubs NeoGenesis products most often appear in at SkinCrew.
Not sure which NeoGenesis products are right for you?
Our clinical skincare specialists can build a complete NeoGenesis regimen matched to your skin and goals, from Cleanser to the right S2RM concentration to Barrier Renewal Cream and SPF.
Talk to a SkinCrew Specialist
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