NeoGenesis Enzyme Cream Mask
- Regular price
- $23.00
- Sale price
- $23.00
- Regular price
NeoGenesis Enzyme Cream Mask exfoliates with two fruit enzymes, bromelain from pineapple and ficin from fig, rather than scrubs or strong acids.
PREFERRED AUTHORIZED RETAILER
ENJOY FREE SHIPPING $99+
PROTECTED & SECURE DELIVERY
-
Description
-
Key Benefits
-
How to use
-
Ingredients
-
Frequently Asked Questions
Description
What is NeoGenesis Enzyme Cream Mask?
NeoGenesis Enzyme Cream Mask is a creamy clay mask that exfoliates with two fruit enzymes, bromelain from pineapple and ficin from fig, instead of grit or strong acids, while kaolin and bentonite clays absorb excess oil and draw impurities out of pores. Niacinamide, jojoba, squalane and raspberry seed oil keep the texture creamy and comfortable. Apply a thin layer to damp, cleansed skin for 3 to 8 minutes, remove with a warm, wet towel, and use one to three times a week. Available at SkinCrew in 50 g ($79), plus a 15 g trial size ($23).
Sourced direct from NeoGenesis: guaranteed authentic, batch-fresh, fast US shipping.
The problem
Dull, rough, congested skin needs exfoliation, and the usual tools are scrubs that create micro-tears, acid masks that sting sensitive skin, or clay masks that dry everything out. Redness-prone and blemish-prone skin in particular tends to react to all three, so it gets exfoliated rarely and looks it.
Fruit enzymes and clay that exfoliate without irritation.
The enzymes gently dissolve the buildup of dead surface cells that leaves skin looking dull, rough or uneven, the clays clear excess oil and congestion, and the cream base keeps the whole thing comfortable, which is why NeoGenesis positions it for sensitive skin as well as blemish-prone and redness-prone skin. Skin is left smoother, softer and more radiant, and the serums that follow absorb better on freshly exfoliated skin.
Key Benefits
How to use
Ingredients
Frequently Asked Questions
45 Day Satisfaction Guarantee with Checkout+
Try your new skincare and devices with confidence.
If you are not satisfied, return them within 45 days for a full refund or exchange.
- Free return labels
- 45 days start on delivery
- 5% bonus cashback
- Protection against damage & theft
To qualify, you must select Checkout+ at purchase.
If not selected, the standard return policy applies.
Recommended Products
You might also like these
Free Shipping
Free US wide shipping for orders $99+.
Authorized Retailer
Our products are 100% genuine, we only sell products we truly believe in.
Earn Cashback
Join The Crew and earn up to 20%* cashback on every purchase. Redeem your rewards for products and save.
Shop with Confidence
Every order is backed by secure shipping and our 45-Day Satisfaction Guarantee.*
NeoGenesis Enzyme Cream Mask: gentle exfoliation for sensitive, congested skin
NeoGenesis Enzyme Cream Mask exfoliates with two fruit enzymes, bromelain from pineapple and ficin from fig, rather than scrubs or strong acids. The enzymes gently dissolve the buildup of dead surface cells that leaves a complexion looking dull, rough or uneven, while kaolin and bentonite clays absorb excess oil and draw impurities out of pores. Skin is left smoother, softer and more radiant, and because the surface is clear, the serums and moisturizers that follow absorb more effectively.
The formula is built to do this without irritation. NeoGenesis recommends it for sensitive skin as well as blemish-prone and redness-prone skin: it calms the look of congestion, helps clear pores and brightens uneven tone, and niacinamide supports the barrier along the way. Jojoba oil, squalane, red raspberry seed oil and vitamin E keep the clay creamy rather than chalky. Skincare professionals use it with or without steam in the treatment room; at home, use it one to three times a week. Available at SkinCrew, an Authorized NeoGenesis US Retailer, with fast US shipping.
🛡️ Authorized NeoGenesis US Retailer Guarantee
NeoGenesis sells through licensed skincare professionals and authorized retailers. SkinCrew sources every unit directly from NeoGenesis, so you receive:
Why Enzyme Cream Mask Stands Out
- How enzyme exfoliation works. Bromelain (pineapple) and ficin (fig) are proteolytic fruit enzymes that loosen the bonds holding dead surface cells in place, so buildup lifts away without the friction of a scrub or the sting of a strong acid.
- Two clays, one job. Kaolin and bentonite absorb excess sebum and lift debris and impurities out of pores, reducing congestion and visibly calming blemish-prone skin while the creamy base prevents over-drying.
- Niacinamide for balance. Niacinamide supports the skin barrier, reduces the look of redness and balances surface oil, with antioxidant support against the environmental stressors associated with dullness and uneven tone.
- A cushioned base. Jojoba seed oil, squalane, red raspberry seed oil, glycerin and vitamin E acetate give the mask its cream texture, so it stays comfortable on sensitive skin for the full 3 to 8 minutes.
| Feature | Enzyme Cream Mask | Acid or scrub exfoliants | Clay-only masks |
|---|---|---|---|
| Exfoliation method | Pineapple and fig enzymes dissolve surface buildup, no grit | Glycolic or lactic acid, or physical scrub particles | Scrub particles or strong clay alone |
| Oil and pores | Kaolin and bentonite absorb oil and draw out impurities | Varies, often none | Clay that can over-dry |
| Sensitive skin fit | Recommended for sensitive, redness-prone and blemish-prone skin | Often too strong for reactive skin | Tightness and stinging are common |
| Texture | Creamy, with jojoba, squalane and raspberry seed oil | Gel or liquid | Chalky, drying clay |
| How to buy | Authorized retailers only, such as SkinCrew | Varies | Mass retail |
The Enzyme Cream Mask Profile
What Enzyme Cream Mask Does
Benefit statements describe the appearance and feel of skin and reflect NeoGenesis product information. Individual results vary.
Who Enzyme Cream Mask Is For
✅ A strong match for
- Dull, rough or uneven texture that wants exfoliation without scrubbing
- Congested pores, excess oil and blemish-prone skin
- Sensitive and redness-prone skin that reacts to acids and physical exfoliants
- Uneven tone and visible signs of aging that benefit from regular, gentle resurfacing
💡 Tolerance and skin type
Made for sensitive skin: the enzymes exfoliate without friction, the clays are cushioned in a creamy base, and NeoGenesis recommends it for redness-prone and blemish-prone skin. Keep to the 3 to 8 minute window and start with once a week.
How to Use Enzyme Cream Mask
Enzyme Cream Mask Ingredient Deep Dive
Fig and Pineapple Enzymes
Ficin (fig) and bromelain (pineapple) are fruit enzymes that gently exfoliate while lifting buildup, supporting a clearer, calmer-looking complexion and improving the appearance of uneven tone and texture.
Kaolin and Bentonite Clay
Absorb excess oil, gently exfoliate and help clear pores by lifting sebum, debris and impurities, reducing congestion and visibly calming blemish-prone skin without over-drying.
Niacinamide
Supports the skin barrier, reduces the look of redness and balances surface oil for a more even-looking complexion, with antioxidant support against the environmental stressors linked to dullness and uneven tone.
Full ingredient list. Water, Caprylic Capric Triglyceride, Glyceryl Stearate, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Simmondsia Chinensis (Jojoba) Seed Oil, Glycerin, Squalane, Cetearyl Alcohol, Bromelain, Niacinamide, Kaolin, Bentonite, Octyldodecanol, Tocopheryl Acetate, Hydroxyethylcellulose, Cera Alba (Beeswax), Rubus Idaeus (Red Raspberry) Seed Oil, C15-19 Alkane, Ficin, Ethylhexylglycerin, Lecithin, 1,2-hexanediol, Caprylyl Glycol, Polyglyceryl-6 Laurate, Polyglycerin-6.
Watch: Enzyme Cream Mask Explained
NeoGenesis made this short product video for Enzyme Cream Mask, so you can see the texture, the application and where it fits in a routine before you buy.
Real Results with Enzyme Cream Mask
NeoGenesis publishes before and after photos from its professional partners. These cases used Enzyme Cream Mask as part of a NeoGenesis routine, and each caption lists every product involved.

Blemish-prone skin. Products used: Cleanser, Recovery, Mandelic Acid 8%, Enzyme Cream Mask.
Photos courtesy of Tara Linville, Doll Face Esthetics OKC. Individual results vary.
Stubborn dark spots. Products used: Cleanser, Booster, Eye Serum, Intensive Moisturizer, Enzyme Cream Mask.
Photos courtesy of NeoGenesis. Individual results vary.My skin is now doing good and the eye area is a lot better.Shared by NeoGenesis

Blemish-prone skin. Products used: Recovery, Booster, Moisturizing Mist, Barrier Renewal Cream and more.
Photos courtesy of Mariam Abbas. Individual results vary.
Blemish-prone skin. Products used: Cleanser, Recovery, Moisturizing Mist, Barrier Renewal Cream and more.
Photos courtesy of Katherine Aalbu-Ruward, Rising Sun Organique. Individual results vary.Photos courtesy of NeoGenesis professional partners. Unretouched photos supplied by the brand. Individual results vary.
The Science Behind S2RM
S2RM stands for stem cell released molecules. NeoGenesis describes it as the complete secretome of human fibroblast and adipose mesenchymal stem cells: the growth factors, peptides, cytokines, antioxidants and extracellular vesicles, including exosomes, that these cells naturally release. The products contain conditioned media, the molecules the cells secrete, and no live cells.
The brand names Dr. Raja Sivamani, a dermatologist, as Head of its Scientific Medical Advisory Board, and describes its products as dermatologist recommended. NeoGenesis states that S2RM is patented and that the technology is made for all skin types.
NeoGenesis also publishes research on its product pages under titles such as the ones below. We quote these as brand statements rather than as SkinCrew claims.
- Systems Therapeutics Approach
- Rescue of Degenerating Cells Using S2RM
- Safety Profile of S2RM Technology
Watch: Why stem cell released molecules are used in skincare
How to Use Enzyme Cream Mask in a NeoGenesis Routine
After cleansing, apply a thin layer over damp skin. Follow with your S2RM serum and moisturizer. Use one to three times a week depending on your skin type.
Step 1: Cleanse
Step 2: Treat
Step 3: Moisturize and Protect
Pairs Well With Enzyme Cream Mask
NeoGenesis builds its routine in layers: cleanse, S2RM serum, targeted step, moisturizer. These are the products the brand pairs with Enzyme Cream Mask.
Browse the full range in the NeoGenesis collection, or shop by concern in Dull skin, Sensitive skin, Oily skin.
Not Sure Where Enzyme Cream Mask Fits in Your Routine?
A SkinCrew skincare expert can tell you which NeoGenesis S2RM concentration suits your skin, how to layer Enzyme Cream Mask with the S2RM serums and what you already use, and what to expect in the first weeks. Consultations are complimentary and we are an Authorized NeoGenesis US Retailer.
Contact Our Skincare ExpertsNeoGenesis Enzyme Cream Mask is a cosmetic product. Statements on this page describe the appearance of skin and reflect NeoGenesis product information. Individual results vary.
NeoGenesis Enzyme Cream Mask FAQ
What does an enzyme face mask do?
An enzyme mask exfoliates by dissolving the buildup of dead surface cells that leaves skin looking dull, rough or uneven, with no scrubbing. NeoGenesis Enzyme Cream Mask combines fruit enzymes with clays and nourishing botanicals to reveal smoother, brighter, better-balanced skin and to help serums absorb more effectively afterward.
Is an enzyme mask good for sensitive skin?
This one is made for it. NeoGenesis formulates Enzyme Cream Mask to exfoliate without irritation and recommends it for sensitive skin, including redness-prone and blemish-prone skin. Skincare professionals use it in the treatment room with or without steam.
Which enzymes are in NeoGenesis Enzyme Cream Mask?
Two: ficin from fig and bromelain from pineapple. They are paired with kaolin and bentonite clays to absorb oil and clear pores, and with niacinamide, jojoba, squalane and raspberry seed oil for barrier support and a creamy, comfortable texture.
How often should I use an enzyme mask?
Most people use one to three times a week depending on skin type. NeoGenesis says regular use of Enzyme Cream Mask maintains smoother-looking skin, improved texture and a brighter complexion without over-exfoliating. Leave it on for 3 to 8 minutes, no longer.
How do I use Enzyme Cream Mask?
After cleansing, apply a thin layer over damp skin and leave it on for 3 to 8 minutes. Remove with a warm, wet towel, then follow with your NeoGenesis serum and moisturizer, which absorb better on freshly exfoliated skin. It comes in 15 g and 50 g.
Are there before and after photos for Enzyme Cream Mask?
Yes. NeoGenesis publishes before and after case photos from its professional partners, and a selection that used Enzyme Cream Mask is shown on this page with every product in the routine listed in the caption. Individual results vary.
Is there a video on how to use Enzyme Cream Mask?
Yes. The NeoGenesis product video on this page walks through Enzyme Cream Mask, what is in it and how to apply it, and the science video explains the stem cell released molecules behind the line.
Is SkinCrew an authorized NeoGenesis retailer in the US?
Yes. SkinCrew is an Authorized NeoGenesis US Retailer and sources every unit directly from NeoGenesis, so Enzyme Cream Mask arrives fresh, authentic and covered by the brand guarantee, with fast US shipping.

