NeoGenesis MB-1
45 Day Guarantee
- Regular price
- $55.00
- Sale price
- $55.00
- Regular price
MB-1 is the NeoGenesis balancing probiotic mist, and NeoGenesis describes it as the only microbiome spray formulated with live probiotic bacteria. Most microbiome skincare uses ferments or inactive extracts.
PREFERRED AUTHORIZED RETAILER
ENJOY FREE SHIPPING $99+
PROTECTED & SECURE DELIVERY
-
Description
-
Key Benefits
-
How to use
-
Ingredients
-
Frequently Asked Questions
Description
What is NeoGenesis MB-1?
NeoGenesis MB-1 is the NeoGenesis balancing probiotic mist, and it is unlike most microbiome skincare: instead of ferments or inactive extracts it contains live nitrifying bacteria, delivered in a three-ingredient formula with water and sodium hyaluronate butyrate. NeoGenesis describes it as the only microbiome spray formulated with live probiotic bacteria, designed to hydrate, support the skin barrier and help restore balance to skin that is blemish-prone, reactive or easily irritated. Shake well and mist it on as the very last step, at least twice a day. Available at SkinCrew in 30 mL ($55) and 120 mL ($169).
Sourced direct from NeoGenesis: guaranteed authentic, batch-fresh, fast US shipping.
The problem
Breakouts, redness, itch and irritation are often signs of a skin microbiome that has lost its balance, and most products make it worse: harsh actives, alcohol-based toners and over-cleansing wipe out the beneficial flora along with everything else. The microbiome products that do exist usually contain ferments or lysates, which are not alive and cannot compete with the bacteria causing trouble.
Live probiotic bacteria, not ferments, for a calmer, clearer-looking complexion.
MB-1 puts live bacteria on the skin so they can support flora diversity through natural microbial competition, while sodium hyaluronate butyrate hydrates and delivers butyrate, a postbiotic associated with comfort and barrier support. Together they help calm the look of redness, breakouts, irritation and itch. Because it must go on last, after every other product, it fits any routine without replacing anything in it.
Key Benefits
How to use
Ingredients
Frequently Asked Questions
45 Day Satisfaction Guarantee with Checkout+
Try your new skincare and devices with confidence.
If you are not satisfied, return them within 45 days for a full refund or exchange.
- Free return labels
- 45 days start on delivery
- 5% bonus cashback
- Protection against damage & theft
To qualify, you must select Checkout+ at purchase.
If not selected, the standard return policy applies.
Recommended Products
You might also like these
Free Shipping
Free US wide shipping for orders $99+.
Authorized Retailer
Our products are 100% genuine, we only sell products we truly believe in.
Earn Cashback
Join The Crew and earn up to 20%* cashback on every purchase. Redeem your rewards for products and save.
Shop with Confidence
Every order is backed by secure shipping and our 45-Day Satisfaction Guarantee.*
NeoGenesis MB-1: the balancing probiotic mist with live bacteria
NeoGenesis MB-1 is the NeoGenesis balancing probiotic mist, and NeoGenesis describes it as the only microbiome spray formulated with live probiotic bacteria. Most microbiome skincare uses ferments or inactive extracts. MB-1 uses live nitrifying bacteria, in a formula of just three ingredients: water, the bacteria and sodium hyaluronate butyrate. It is designed to hydrate, support the skin barrier and help restore balance to blemish-prone, reactive and easily irritated skin, for a calmer, clearer-looking complexion.
The live bacteria help support a balanced skin microbiome by encouraging flora diversity and natural microbial competition. Sodium hyaluronate butyrate, a skin-native hyaluronic acid, hydrates and delivers butyrate, a postbiotic associated with comfort and barrier support. Together they help calm the look of redness, breakouts, irritation and itch. Shake well and spray it on as the last step of your routine, morning and evening at minimum, and as often as your skin wants during the day. Available at SkinCrew, an Authorized NeoGenesis US Retailer, with fast US shipping.
🛡️ Authorized NeoGenesis US Retailer Guarantee
NeoGenesis sells through licensed skincare professionals and authorized retailers. SkinCrew sources every unit directly from NeoGenesis, so you receive:
Why MB-1 Stands Out
- The skin microbiome. An ecosystem of microorganisms lives on the surface of the skin. MB-1 is designed to help support a balanced microbiome as part of a daily routine.
- Why live nitrifying bacteria. Live bacteria encourage flora diversity and natural microbial competition, which is how MB-1 helps maintain a balanced skin environment and calmer, more resilient skin.
- Butyrate, a postbiotic. Sodium hyaluronate butyrate hydrates like hyaluronic acid and delivers butyrate, associated with calming the look of redness, improving comfort and supporting the barrier.
- Handling a living formula. Because the bacteria are alive, MB-1 is shaken before use, stored at room temperature or cooler, kept out of direct sunlight and used within six months of opening.
| Feature | MB-1 | Ferment or lysate probiotics | Prebiotic mists |
|---|---|---|---|
| Probiotic format | Live nitrifying bacteria | Probiotic ferments or lysates (inactive) | Prebiotic sugars or ferment extracts |
| Ingredient list | Three ingredients: water, live bacteria, sodium hyaluronate butyrate | Long lists with preservatives and fragrance | Long lists with preservatives and fragrance |
| Hydration | Sodium hyaluronate butyrate, a skin-native hyaluronic acid with a postbiotic | Standard humectants | Standard humectants |
| Routine fit | Final step after all other products, twice daily or as needed | Varies | Varies |
| How to buy | Authorized retailers only, such as SkinCrew | Varies | Mass retail |
The MB-1 Profile
What MB-1 Does
Benefit statements describe the appearance and feel of skin and reflect NeoGenesis product information. Individual results vary.
Who MB-1 Is For
✅ A strong match for
- Skin that is red, reactive or easily irritated
- Blemish-prone or congested skin, including oily skin
- Dry, itchy-feeling or sensitive skin
- Anyone who wants to support the skin barrier and microbiome as a final daily step
💡 Tolerance and skin type
Made for all skin types, including sensitive and reactive skin, with a fragrance-free, three-ingredient formula. NeoGenesis advises not to use it on skin that is broken or open.
How to Use MB-1
MB-1 Ingredient Deep Dive
Live Probiotic Bacteria
Advanced live nitrifying bacteria that help support a balanced skin microbiome by encouraging flora diversity and natural microbial competition, promoting calmer, more resilient skin that is less prone to irritation and imbalance.
Sodium Hyaluronate Butyrate
A skin-native form of hyaluronic acid that hydrates while delivering butyrate, a beneficial postbiotic associated with calming the look of redness, improving skin comfort and supporting the skin barrier.
Water, and nothing else
The full ingredient list is water, live nitrifying bacteria and sodium hyaluronate butyrate. There is no fragrance and no filler, and because the bacteria are alive, storage and the six-month use window matter.
Full ingredient list. Water, Live Nitrifying Bacteria, Sodium Hyaluronate Butyrate
Watch: MB-1 Explained
NeoGenesis made this short product video for MB-1, so you can see the texture, the application and where it fits in a routine before you buy.
Real Results with MB-1
NeoGenesis publishes before and after photos from its professional partners. These cases used MB-1 as part of a NeoGenesis routine, and each caption lists every product involved.
Dark spots and uneven tone. Products used: Cleanser, Recovery, Skin Serum, MB-1.
Photos courtesy of NeoGenesis. Individual results vary.She now has a glow!Shared by NeoGenesis
Blemish-prone skin. Products used: Cleanser, Recovery, Salicylic Acid Gel and more.
Photos courtesy of Mary Reed, Esteem Skin Clinic. Individual results vary.
Post-blemish marks. Products used: Cleanser, Recovery, Mandelic Acid 8% and more.
Photos courtesy of Ellen Lam, Ellen's Place. Individual results vary.
Blemish-prone skin. Products used: Cleanser, Recovery, Eye Serum, Mandelic Acid 8% and more.
Photos courtesy of Jennalee Dahlen. Individual results vary.Photos courtesy of NeoGenesis professional partners. Unretouched photos supplied by the brand. Individual results vary.
The Science Behind S2RM
S2RM stands for stem cell released molecules. NeoGenesis describes it as the complete secretome of human fibroblast and adipose mesenchymal stem cells: the growth factors, peptides, cytokines, antioxidants and extracellular vesicles, including exosomes, that these cells naturally release. The products contain conditioned media, the molecules the cells secrete, and no live cells.
The brand names Dr. Raja Sivamani, a dermatologist, as Head of its Scientific Medical Advisory Board, and describes its products as dermatologist recommended. NeoGenesis states that S2RM is patented and that the technology is made for all skin types.
NeoGenesis also publishes research on its product pages under titles such as the ones below. We quote these as brand statements rather than as SkinCrew claims.
- Systems Therapeutics Approach
- Rescue of Degenerating Cells Using S2RM
- Safety Profile of S2RM Technology
Watch: Understanding the S2RM secretome
How to Use MB-1 in a NeoGenesis Routine
Shake well before each use. Do not use on skin that is broken or open. Store at room temperature (max 25 C / 77 F) or cooler, away from direct sunlight, and use within 6 months of opening.
Step 1: Cleanse
Step 2: Treat
Step 3: Moisturize and Protect
Pairs Well With MB-1
NeoGenesis builds its routine in layers: cleanse, S2RM serum, targeted step, moisturizer. These are the products the brand pairs with MB-1.
Browse the full range in the NeoGenesis collection, or shop by concern in Sensitive skin, Oily skin, What's new.
Not Sure Where MB-1 Fits in Your Routine?
A SkinCrew skincare expert can tell you which NeoGenesis S2RM concentration suits your skin, how to layer MB-1 with the S2RM serums and what you already use, and what to expect in the first weeks. Consultations are complimentary and we are an Authorized NeoGenesis US Retailer.
Contact Our Skincare ExpertsNeoGenesis MB-1 is a cosmetic product. It contains live probiotic bacteria and no stem cells. Statements on this page describe the appearance of skin and reflect NeoGenesis product information. Individual results vary.
NeoGenesis MB-1 FAQ
What is NeoGenesis MB-1?
MB-1 is a balancing probiotic mist that NeoGenesis describes as the only microbiome spray formulated with live probiotic bacteria. It contains three ingredients: water, live nitrifying bacteria and sodium hyaluronate butyrate. It is designed to hydrate, support the skin barrier and help restore balance to blemish-prone, reactive and easily irritated skin for a calmer, clearer-looking complexion.
How do I use MB-1?
Shake well before each use. Spray MB-1 on the skin after all other products have been applied, so it is the final step of your routine. Use it at least twice a day, or as needed during the day. Do not use it on skin that is broken or open. Store at room temperature (max 25 C / 77 F) or cooler, out of direct sunlight, and use within 6 months of opening.
Who is MB-1 for?
NeoGenesis positions MB-1 for skin that is blemish-prone, reactive or easily irritated, for oily skin, sensitive skin and dry skin. It suits anyone dealing with the look of redness, breakouts, irritation or itch, and anyone who wants to support the skin barrier and microbiome as an everyday step. It is made for all skin types.
What is the difference between MB-1 and MB-2?
MB-1 is a lightweight microbiome mist made with live nitrifying bacteria to help maintain a balanced skin environment during the day. MB-2 Probiotic Balm combines multiple probiotic strains with nourishing botanical oils to help prevent moisture loss in the evening. Many people use both: MB-1 as the last step in the morning and MB-2 at night.
How is MB-1 different from other probiotic skincare?
Most microbiome products use probiotic ferments, lysates or other inactive ingredients. MB-1 features live bacteria designed to support the skin's natural microbiome through flora diversity and natural microbial competition, paired with sodium hyaluronate butyrate for hydration. That is also why it is stored carefully and used within six months of opening.
Can I use MB-1 with retinoids, acids or other serums?
Yes. MB-1 goes on after everything else, so apply your S2RM serum, any actives and your moisturizer first, then spray MB-1 as the final layer. NeoGenesis lists Barrier Renewal Cream, Recovery, Intensive Moisturizer and Skin Serum as its pairings. Because it is a living formula, give the products underneath a moment to absorb before misting.
Are there before and after photos for MB-1?
Yes. NeoGenesis publishes before and after case photos from its professional partners, and a selection that used MB-1 is shown on this page with every product in the routine listed in the caption. Individual results vary.
Is there a video on how to use MB-1?
Yes. The NeoGenesis product video on this page walks through MB-1, what is in it and how to apply it, and the science video explains the stem cell released molecules behind the line.
Is SkinCrew an authorized NeoGenesis retailer in the US?
Yes. SkinCrew is an Authorized NeoGenesis US Retailer and sources every unit directly from NeoGenesis, so MB-1 arrives fresh, authentic and covered by the brand guarantee, with fast US shipping.