NeoGenesis Mandelic Acid 8%

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NeoGenesis Mandelic Acid 8% is a lightweight exfoliating gel made for hyperpigmented, dry or blemish-prone skin.

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NeoGenesis Mandelic Acid 8% (15mL)
NeoGenesis Mandelic Acid 8% (30mL)
NeoGenesis Mandelic Acid 8% (5mL)
  • NeoGenesis Mandelic Acid 8% (15mL)
  • NeoGenesis Mandelic Acid 8% (30mL)
  • NeoGenesis Mandelic Acid 8% (5mL)
NeoGenesis Mandelic Acid 8% (15mL)
NeoGenesis Mandelic Acid 8% (30mL)
NeoGenesis Mandelic Acid 8% (5mL)
  • Description

  • Key Benefits

  • How to use

  • Ingredients

  • Frequently Asked Questions

Description

NeoGenesis · Mandelic Acid 8%

What is NeoGenesis Mandelic Acid 8%?

NeoGenesis Mandelic Acid 8% is a lightweight exfoliating gel for hyperpigmented, dry or blemish-prone skin. Mandelic acid is an alpha hydroxy acid with a larger molecular size than most AHAs, which makes for a gentler exfoliation that suits sensitive and reactive skin, and sodium PCA and glycerin, both natural moisturizing factors, hydrate as it works. Use it in the evening after cleansing and your S2RM serum, follow with moisturizer, and wear sunscreen daily. Available at SkinCrew in 15 mL ($48) and 30 mL ($67), plus a 5 mL trial size ($13).

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The problem

Glycolic and lactic acids are effective, and for sensitive, dry or darker skin they are frequently too much: stinging, flaking and the rebound redness or marks that follow. People who need exfoliation most for uneven tone and post-blemish marks are often the ones who tolerate the standard AHAs least.

The gentle AHA that hydrates, brightens and refines.

Mandelic acid's larger molecule penetrates more slowly and evenly, so Mandelic Acid 8% refines rough texture, gradually improves the look of uneven pigmentation and post-blemish marks and smooths the appearance of fine lines without the harsh, stripped feeling of many mandelic formulas. It keeps pores clear and calms the look of breakouts while promoting a clearer, brighter, more radiant complexion, and the humectants support the barrier alongside the acid.

Key Benefits

How to use

Ingredients

Frequently Asked Questions

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NeoGenesis Mandelic Acid 8%: the gentle AHA for brighter, smoother, clearer skin

NeoGenesis Mandelic Acid 8% is a lightweight exfoliating gel made for hyperpigmented, dry or blemish-prone skin. Mandelic acid is an alpha hydroxy acid with a larger molecular size than most AHAs, which gives a gentler exfoliation experience and makes it a good fit for sensitive and reactive skin. It gently lifts dull surface cells to refine rough texture, gradually improve the look of uneven pigmentation, discoloration and post-blemish marks, and smooth the appearance of fine lines.

It also keeps pores clear, reducing the appearance of congestion and excess oil, and calms the look of breakouts for a clearer, more radiant complexion. What sets it apart from many mandelic formulas is the absence of that harsh, stripped feeling: sodium PCA and glycerin, both natural moisturizing factors, hydrate and support the barrier alongside the acid. Apply in the evening after your S2RM serum, follow with moisturizer, and wear sunscreen daily. Available at SkinCrew, an Authorized NeoGenesis US Retailer, with fast US shipping.

🛡️ Authorized NeoGenesis US Retailer Guarantee

NeoGenesis sells through licensed skincare professionals and authorized retailers. SkinCrew sources every unit directly from NeoGenesis, so you receive:

✅ 100% AuthenticDirect supply from NeoGenesis, never diverted, expired or grey-market stock.
❄️ Fresh, Potent FormulasNeoGenesis formulas are only as good as their handling. Batch-fresh stock, stored and shipped with care, so Mandelic Acid 8% arrives at full strength.

Why Mandelic Acid 8% Stands Out

  • Why mandelic acid. Mandelic acid is an alpha hydroxy acid that exfoliates the surface of the skin. Its larger molecular size slows how it moves into skin, which is why NeoGenesis positions it as the gentler AHA for sensitive, dry and mature skin.
  • Tone and texture. By lifting dull, uneven surface cells it improves the appearance of rough texture, dullness, fine lines and post-blemish discoloration, leaving skin looking smoother, brighter and more refined.
  • Natural moisturizing factors. Sodium PCA is a powerful humectant that attracts and retains water in the outer skin layer, supporting lasting hydration and barrier function while the acid works.
  • Glycerin and the barrier. Glycerin acts as a prebiotic and is clinically shown to increase hydration and reduce transepidermal water loss, supporting a smoother, more resilient skin surface.
MANDELIC ACID 8% VS GLYCOLIC OR LACTIC ACID SERUMS VS DRYING AHA TREATMENTS
FeatureMandelic Acid 8%Glycolic or lactic acid serumsDrying AHA treatments
Acid type8% mandelic acid, a large-molecule AHA for gentle exfoliationGlycolic or lactic acid, smaller molecules that work faster and harderGlycolic acid, often in a drying base
Sensitive skin fitMade for sensitive, reactive, dry and mature skinOften too strong for reactive skinStinging and flaking are common
HydrationSodium PCA and glycerin hydrate and support the barrierVaries by formulaMinimal, often stripping
Routine fitEvenings, after an S2RM serum and before moisturizerStandaloneStandalone
How to buyAuthorized retailers only, such as SkinCrewVariesMass retail

The Mandelic Acid 8% Profile

Technology
The gentle AHA
Mandelic acid's larger molecular size means a gentler exfoliation than most alpha hydroxy acids, so reactive skin can use it.
Formula
Brightens tone and marks
Gradually improves the look of dark spots, uneven pigmentation and post-blemish discoloration for a more even complexion.
Results
Clears and calms
Keeps pores clear, reduces the appearance of congestion and calms the look of breakouts in blemish-prone skin.
Fit
Hydrates as it exfoliates
Sodium PCA and glycerin, natural moisturizing factors, support hydration and the barrier, so there is no stripped feeling.

What Mandelic Acid 8% Does

Gently exfoliates to smooth rough, uneven texture
Brightens the look of dark spots, discoloration and post-blemish marks
Keeps pores clear and calms the look of breakouts
Smooths the appearance of fine lines and dullness
Hydrates and supports the barrier while it exfoliates
Gentle enough for sensitive, reactive, dry and mature skin

Benefit statements describe the appearance and feel of skin and reflect NeoGenesis product information. Individual results vary.

Who Mandelic Acid 8% Is For

✅ A strong match for

  • Uneven skin tone, dark spots and post-blemish marks that need gradual, gentle brightening
  • Rough texture and dullness on dry, mature or sensitive-looking skin
  • Blemish-prone skin that finds stronger exfoliants too harsh or drying
  • Early visible signs of aging, including fine lines and loss of radiance

💡 Tolerance and skin type

Formulated for sensitive and reactive skin: mandelic acid's larger molecule exfoliates more gently than most AHAs, and the hydrating base avoids the stripped feeling. Start with evenings only, layer it over an S2RM serum, and wear sunscreen every day since it increases sun sensitivity.

How to Use Mandelic Acid 8%

Step 1In the evening, cleanse and apply your S2RM serum (Recovery, Booster or Skin Serum).
Step 2Apply 1 pump of Mandelic Acid 8% to the face and allow it to absorb, then follow with moisturizer.
Step 3Use sunscreen daily, as this product increases skin sensitivity to the sun.

Mandelic Acid 8% Ingredient Deep Dive

Mandelic Acid

An alpha hydroxy acid with a larger molecular size than most AHAs. Gently exfoliates to refine texture, improve the appearance of post-blemish discoloration and promote a more even tone with minimal risk of irritation.

Sodium PCA

A natural moisturizing factor (NMF) component and powerful humectant that attracts and holds water in the outer layer of the skin, supporting lasting hydration and barrier function.

Glycerin

Acts as a prebiotic and is clinically shown to increase skin hydration and reduce transepidermal water loss (TEWL), supporting the barrier for smoother, more resilient skin.

Full ingredient list. Water, Propanediol, Mandelic Acid, Glycerin, Sodium PCA, Hydrolyzed Rice Protein, Hydroxyethylcellulose, Benzyl Alcohol, Dehydroacetic Acid, Lactic Acid.

Watch: Mandelic Acid 8% Explained

NeoGenesis made this short product video for Mandelic Acid 8%, so you can see the texture, the application and where it fits in a routine before you buy.

Real Results with Mandelic Acid 8%

NeoGenesis publishes before and after photos from its professional partners. These cases used Mandelic Acid 8% as part of a NeoGenesis routine, and each caption lists every product involved.

Blemish-prone skin. Products used: Recovery, Mandelic Acid 8%, Skin Restore Serum, Barrier Renewal Cream. Photos courtesy of NeoGenesis.

Blemish-prone skin. Products used: Recovery, Mandelic Acid 8%, Skin Restore Serum, Barrier Renewal Cream.

Photos courtesy of Christine Simmons, Skin Discovery. Individual results vary.
Blemish-prone skin. Products used: Cleanser, Recovery, Mandelic Acid 8%, Enzyme Cream Mask. Photos courtesy of NeoGenesis.

Blemish-prone skin. Products used: Cleanser, Recovery, Mandelic Acid 8%, Enzyme Cream Mask.

Photos courtesy of Tara Linville, Doll Face Esthetics OKC. Individual results vary.
Visible signs of aging, neck. Products used: Cleanser, Recovery, Mandelic Acid 8% and more. Photos courtesy of Lisa Brascho.

Visible signs of aging, neck. Products used: Cleanser, Recovery, Mandelic Acid 8% and more.

Photos courtesy of Lisa Brascho. Individual results vary.
Stubborn dark spots. Products used: Skin Serum, Vibrant C Serum, Recovery, Mandelic Acid 8% and more. Photos courtesy of NeoGenesis.

Stubborn dark spots. Products used: Skin Serum, Vibrant C Serum, Recovery, Mandelic Acid 8% and more.

Photos courtesy of Tara Farrar, Emerald Studio for Permanent Makeup. Individual results vary.

Photos courtesy of NeoGenesis professional partners. Unretouched photos supplied by the brand. Individual results vary.

The Science Behind S2RM

S2RM stands for stem cell released molecules. NeoGenesis describes it as the complete secretome of human fibroblast and adipose mesenchymal stem cells: the growth factors, peptides, cytokines, antioxidants and extracellular vesicles, including exosomes, that these cells naturally release. The products contain conditioned media, the molecules the cells secrete, and no live cells.

The brand names Dr. Raja Sivamani, a dermatologist, as Head of its Scientific Medical Advisory Board, and describes its products as dermatologist recommended. NeoGenesis states that S2RM is patented and that the technology is made for all skin types.

NeoGenesis also publishes research on its product pages under titles such as the ones below. We quote these as brand statements rather than as SkinCrew claims.

  • Systems Therapeutics Approach
  • Rescue of Degenerating Cells Using S2RM
  • Safety Profile of S2RM Technology

Watch: Why stem cell released molecules are used in skincare

How to Use Mandelic Acid 8% in a NeoGenesis Routine

In the evening, cleanse and apply your S2RM serum (Recovery, Booster or Skin Serum). Use sunscreen daily, as this product increases skin sensitivity to the sun.

Step 1: Cleanse

CleanserpH-balanced gel that removes the day without stripping the barrier.
Erase The DayEye and lip makeup first, when you wear it.

Step 2: Treat

Mandelic Acid 8%Apply 1 pump of Mandelic Acid 8% to the face and allow it to absorb, then follow with moisturizer.
RecoveryThe highest potency NeoGenesis serum: 70% S2RM for aging, reactive and stressed skin.
Skin Restore SerumHPR vitamin A with carotenoids: smoother, brighter, clearer-looking skin without the retinol irritation.

Step 3: Moisturize and Protect

Barrier Renewal CreamTriple Lipid Technology plus Natural Moisturizing Factors for sensitive, compromised and post-procedure skin.
Mineral sunscreenBroad spectrum SPF every morning, essential with any exfoliating acid or retinoid.
💬

Not Sure Where Mandelic Acid 8% Fits in Your Routine?

A SkinCrew skincare expert can tell you which NeoGenesis S2RM concentration suits your skin, how to layer Mandelic Acid 8% with the S2RM serums and what you already use, and what to expect in the first weeks. Consultations are complimentary and we are an Authorized NeoGenesis US Retailer.

Contact Our Skincare Experts

NeoGenesis Mandelic Acid 8% is a cosmetic product. This product may increase sun sensitivity: use a broad spectrum sunscreen, wear protective clothing and limit sun exposure while using it. Statements on this page describe the appearance of skin and reflect NeoGenesis product information. Individual results vary.

NeoGenesis Mandelic Acid 8% FAQ

What does mandelic acid do for skin?

Mandelic acid is an alpha hydroxy acid (AHA) that gently exfoliates the surface of the skin. NeoGenesis Mandelic Acid 8% uses it to improve the appearance of uneven tone, rough texture, dullness, fine lines and post-blemish discoloration, leaving skin looking smoother, brighter and more refined.

Is mandelic acid good for sensitive skin?

Yes. Mandelic acid has a larger molecular size than many other alpha hydroxy acids, which gives a gentler exfoliation experience. NeoGenesis formulates Mandelic Acid 8% in a hydrating gel with sodium PCA and glycerin, and recommends it especially for dry, mature or sensitive-looking skin.

Does mandelic acid help with dark spots and post-blemish marks?

It is one of the main reasons to use it. By gently refining and smoothing the skin, Mandelic Acid 8% gradually improves the look of uneven pigmentation, discoloration and post-breakout marks, promoting a brighter, more even-looking complexion over time. Consistency and daily sunscreen matter.

How do I use NeoGenesis Mandelic Acid 8%?

In the evening, after cleansing and applying your S2RM serum, apply one pump to the face and allow it to absorb. Follow with moisturizer. Use sunscreen every day, because this product increases your skin's sensitivity to the sun.

Can I use mandelic acid if I get breakouts?

Yes. Mandelic Acid 8% is made for blemish-prone skin as well as dry and hyperpigmented skin. It keeps pores clear by gently exfoliating the surface, reduces the appearance of congestion and excess oil, and calms the look of breakouts, without the harsh, stripped feeling of many mandelic formulas.

What is the difference between Mandelic Acid 8% and Salicylic Acid Gel?

Both are NeoGenesis exfoliants designed to follow an S2RM serum. Mandelic Acid 8% is a gentle alpha hydroxy acid for uneven tone, dullness, post-blemish marks and early signs of aging on dry, mature or sensitive skin. Salicylic Acid Gel is a 2% beta hydroxy acid that works inside the pore, for blackheads, excess oil and congestion.

Are there before and after photos for Mandelic Acid 8%?

Yes. NeoGenesis publishes before and after case photos from its professional partners, and a selection that used Mandelic Acid 8% is shown on this page with every product in the routine listed in the caption. Individual results vary.

Is there a video on how to use Mandelic Acid 8%?

Yes. The NeoGenesis product video on this page walks through Mandelic Acid 8%, what is in it and how to apply it, and the science video explains the stem cell released molecules behind the line.

Is SkinCrew an authorized NeoGenesis retailer in the US?

Yes. SkinCrew is an Authorized NeoGenesis US Retailer and sources every unit directly from NeoGenesis, so Mandelic Acid 8% arrives fresh, authentic and covered by the brand guarantee, with fast US shipping.