NeoGenesis Booster
- Regular price
- $57.50
- Sale price
- $57.50
- Regular price
Booster pairs patented S2RM technology at 40% with sodium hyaluronate butyrate, a high-performance, bioavailable form of hyaluronic acid, and silk amino acids.
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Description
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Ingredients
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Frequently Asked Questions
Description
What is NeoGenesis Booster?
NeoGenesis Booster is the NeoGenesis renewal serum: patented S2RM technology at 40% combined with sodium hyaluronate butyrate, a high-performance, bioavailable form of hyaluronic acid, and silk amino acids. NeoGenesis built it to improve the appearance of dryness, fine lines and uneven tone for a firmer, brighter-looking complexion while delivering deep hydration in one lightweight serum. Dermatologist recommended and made for all skin types, it is applied to damp skin after cleansing, morning or evening. Available at SkinCrew in 15 mL ($156.50) and 30 mL ($265), plus a 5 mL trial size ($57.50).
Sourced direct from NeoGenesis: guaranteed authentic, batch-fresh, fast US shipping.
The problem
Dry, crepey, early-aging skin usually gets two separate answers: a hyaluronic acid serum for hydration and a treatment serum for lines and firmness. Standard hyaluronic acid mostly sits on the surface, and most treatment serums do nothing for moisture, so the two never quite add up, and reactive skin often cannot tolerate the actives in the second bottle.
40% S2RM plus a bioavailable hyaluronic acid, in one step.
Booster pairs the S2RM secretome with a butyrate form of hyaluronic acid that the skin can use more readily, so hydration and renewal happen in the same layer. Growth factors and peptides support the skin's structural matrix to visibly firm crepey skin and soften fine lines, targeted molecules help calm pigment production for a more balanced tone, and silk amino acids leave skin smooth and supple. It is the daily serum for preventative care and for skin that is already showing its age.
Key Benefits
How to use
Ingredients
Frequently Asked Questions
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NeoGenesis Booster: 40% S2RM, the hydrating renewal serum
NeoGenesis Booster pairs patented S2RM technology at 40% with sodium hyaluronate butyrate, a high-performance, bioavailable form of hyaluronic acid, and silk amino acids. S2RM, stem cell released molecules, is the complete secretome from human fibroblast and adipose mesenchymal stem cells, so the growth factors and peptides that support the skin's natural renewal arrive alongside deep, lasting hydration. NeoGenesis designed it to address the visible signs of aging while delivering immediate and long-term cosmetic benefits in one lightweight serum.
It is the serum to reach for when skin looks dry, tight, crepey or uneven. Booster supports the skin's structural matrix to visibly firm and smooth, softens the look of fine lines and wrinkles, and helps calm pigment production for a brighter, more balanced tone. Dermatologist recommended and made for all skin types, it goes on damp skin after cleansing, morning or evening, and works equally well for preventative care or for mature skin. Available at SkinCrew, an Authorized NeoGenesis US Retailer, with fast US shipping.
🛡️ Authorized NeoGenesis US Retailer Guarantee
NeoGenesis sells through licensed skincare professionals and authorized retailers. SkinCrew sources every unit directly from NeoGenesis, so you receive:
Why Booster Stands Out
- The S2RM secretome. Growth factors, peptides and other signaling molecules released by fibroblast and adipose mesenchymal stem cells support the skin's natural renewal processes, resilience and the appearance of damage.
- Hydration with metabolic support. Sodium hyaluronate butyrate is a unique hyaluronic acid that hydrates deeply and delivers butyrate, which supports cellular metabolism and helps skin maintain optimal moisture levels.
- Amino acids for structure. Silk amino acids are the building blocks of skin structure, supporting collagen and glycosaminoglycan synthesis for the look of firmness and elasticity.
- Supporting botanicals. Rose geranium water, hydrolyzed baobab seed extract and Chinese senna seed extract round out a lightweight, layerable formula that respects the skin barrier.
| Feature | Booster | Single growth factor serums | Standard hyaluronic acid serums |
|---|---|---|---|
| Active technology | Patented S2RM at 40% plus sodium hyaluronate butyrate and silk amino acids | One growth factor or a narrow blend | Standard hyaluronic acid, no growth factor content |
| Hydration | Deep, lasting hydration from a bioavailable hyaluronic acid with metabolic support | Often minimal, growth factor only | Surface hydration |
| Firmness and tone | Visibly firms crepey skin, softens lines and evens tone | Usually firmness only | Plumping effect while hydrated |
| Routine fit | Damp skin after cleansing, AM or PM, layers under moisturizer and sunscreen | Once or twice daily | Once or twice daily |
| How to buy | Authorized retailers only, such as SkinCrew | Varies | Mass retail |
The Booster Profile
What Booster Does
Benefit statements describe the appearance and feel of skin and reflect NeoGenesis product information. Individual results vary.
Who Booster Is For
✅ A strong match for
- Skin that feels dry, tight or dehydrated
- Fine lines, wrinkles and early loss of firmness
- Uneven tone, dark spots and discoloration
- Anyone starting preventative age management, and mature skin that wants hydration with its actives
💡 Tolerance and skin type
Dermatologist recommended and made for all skin types. Booster is lightweight and free of retinoids and exfoliating acids, so it can be introduced straight into a daily routine; those with reactive skin can start once a day and build to twice.
How to Use Booster
Booster Ingredient Deep Dive
Human Stem Cell Conditioned Media
The fresh secretome from human fibroblast and adipose mesenchymal stem cells: released molecules from exosomes, ectosomes and the soluble fraction that help skin return to a more balanced, youthful-looking state. This is the S2RM technology, at 40% in Booster.
Sodium Hyaluronate Butyrate
A unique hyaluronic acid molecule that delivers deep hydration together with metabolic support. Butyrate is a key energy source for skin cells, supporting cellular metabolism so skin can maintain optimal moisture levels and its natural renewal.
Silk Amino Acids
The fundamental building blocks of skin structure. They support collagen and glycosaminoglycan (GAG) synthesis, helping improve the look of firmness, elasticity and overall skin integrity.
Full ingredient list. Water, Human Adipose Mesenchymal Stem Cell Conditioned Media, Human Fibroblast Conditioned Media, Rose Geranium (Pelargonium spp.) Water, Glycerin, Potassium Citrate, Gluconolactone, Xanthan Gum, Silk Amino Acids, Hydrolyzed Baobab (Adansonia Digitata) Seed Extract, Sodium Benzoate, Glyceryl Polyacrylate, Sodium Hyaluronate Butyrate, Chinese Senna (Cassia Obtusifolia) Seed Extract.
Watch: Booster Explained
NeoGenesis made this short product video for Booster, so you can see the texture, the application and where it fits in a routine before you buy.
Real Results with Booster
NeoGenesis publishes before and after photos from its professional partners. These cases used Booster as part of a NeoGenesis routine, and each caption lists every product involved.

Stubborn dark spots. Products used: Cleanser, Booster, Eye Serum, Intensive Moisturizer, Enzyme Cream Mask.
Photos courtesy of NeoGenesis. Individual results vary.My skin is now doing good and the eye area is a lot better.Shared by NeoGenesis

Blemish-prone skin. Products used: Recovery, Booster, Moisturizing Mist, Barrier Renewal Cream and more.
Photos courtesy of Mariam Abbas. Individual results vary.
Blemish-prone skin. Products used: Cleanser, Booster, Recovery, Light Moisturizer and more.
Photos courtesy of NeoGenesis. Individual results vary.Her forehead is smooth and the pores appear smaller.Shared by NeoGenesis
Photos courtesy of NeoGenesis professional partners. Unretouched photos supplied by the brand. Individual results vary.
The Science Behind S2RM
S2RM stands for stem cell released molecules. NeoGenesis describes it as the complete secretome of human fibroblast and adipose mesenchymal stem cells: the growth factors, peptides, cytokines, antioxidants and extracellular vesicles, including exosomes, that these cells naturally release. The products contain conditioned media, the molecules the cells secrete, and no live cells.
The brand names Dr. Raja Sivamani, a dermatologist, as Head of its Scientific Medical Advisory Board, and describes its products as dermatologist recommended. NeoGenesis states that S2RM is patented and that the technology is made for all skin types.
NeoGenesis also publishes research on its product pages under titles such as the ones below. We quote these as brand statements rather than as SkinCrew claims.
- Systems Therapeutics Approach
- Rescue of Degenerating Cells Using S2RM
- Safety Profile of S2RM Technology
Watch: Understanding the S2RM secretome
How to Use Booster in a NeoGenesis Routine
After cleansing, apply Booster to damp skin. Use morning or evening, or both. For an S2RM routine that layers products, Recovery or Booster goes on first, then targeted serums such as Eye Serum or Skin Restore Serum.
Step 1: Cleanse
Step 2: Treat
Step 3: Moisturize and Protect
Pairs Well With Booster
NeoGenesis builds its routine in layers: cleanse, S2RM serum, targeted step, moisturizer. These are the products the brand pairs with Booster.
Browse the full range in the NeoGenesis collection, or shop by concern in Anti-aging, Dry skin, Dull skin.
Shop Related Skincare
The brand, category and concern pages this product belongs to at SkinCrew.
Read the Guides
Side-by-side comparisons and brand guides from The Skin Edit.
Not Sure Where Booster Fits in Your Routine?
A SkinCrew skincare expert can tell you which NeoGenesis S2RM concentration suits your skin, how to layer Booster with the S2RM serums and what you already use, and what to expect in the first weeks. Consultations are complimentary and we are an Authorized NeoGenesis US Retailer.
Contact Our Skincare ExpertsNeoGenesis Booster is a cosmetic product. NeoGenesis S2RM products contain conditioned media, the molecules released by cells, and no live cells. Statements on this page describe the appearance of skin and reflect NeoGenesis product information. Individual results vary.
NeoGenesis Booster FAQ
What is NeoGenesis Booster serum?
Booster is the NeoGenesis renewal serum. It combines patented S2RM technology at 40% with sodium hyaluronate butyrate, a bioavailable form of hyaluronic acid, and silk amino acids. It is designed to improve the appearance of dryness, fine lines and uneven tone for a firmer, brighter-looking complexion while delivering deep hydration, with immediate and long-term cosmetic benefits in one lightweight serum.
How do I use Booster?
After cleansing, apply Booster to damp skin, then follow immediately with moisturizer and/or sunscreen. It can be used morning or evening, or both, as part of your daily routine. If you use other NeoGenesis serums such as Eye Serum or Skin Restore Serum, apply Booster first and layer those over it.
Who is Booster for?
Booster suits skin that feels dry or tight, skin showing fine lines, wrinkles or loss of firmness, and skin with uneven tone or discoloration. NeoGenesis also recommends it for preventative aging, because it supports texture, firmness, radiance and long-term skin quality before deeper changes develop. It is dermatologist recommended and made for all skin types.
How is Booster different from Recovery and Skin Serum?
All three are S2RM serums at different strengths. Recovery is 70% S2RM, the highest potency, for correction and stressed or compromised skin. Booster is 40% S2RM with added hyaluronic acid and amino acids, so it is the choice when hydration and firmness are the priority. Skin Serum is 20% S2RM, a lightweight daily essential for early signs of aging, sensitive skin and larger areas.
What is sodium hyaluronate butyrate?
It is a unique hyaluronic acid molecule that attracts and retains moisture while supporting the skin's protective barrier. The butyrate portion is a key energy source for skin cells, supporting cellular metabolism. In Booster it works alongside S2RM technology to help improve the appearance of mature skin and overall skin quality.
How long until I see results?
NeoGenesis does not publish a fixed timeline. The brand describes Booster as delivering immediate cosmetic benefits, mainly hydration and a smoother feel, and long-term benefits to the appearance of fine lines, wrinkles and firmness with consistent daily use. Use it every day, morning or evening, for the best chance of seeing those longer-term changes.
Can I use Booster with retinoids, vitamin C or exfoliating acids?
Yes. NeoGenesis designs its targeted products, including Skin Restore Serum (vitamin A), Vibrant C Serum and Mandelic Acid 8%, to be applied after an S2RM serum. Apply Booster to damp skin first, let it absorb, then layer the active, and finish with moisturizer and/or sunscreen. Wear sunscreen daily, especially when using exfoliating acids.
Are there before and after photos for Booster?
Yes. NeoGenesis publishes before and after case photos from its professional partners, and a selection that used Booster is shown on this page with every product in the routine listed in the caption. Individual results vary.
Is there a video on how to use Booster?
Yes. The NeoGenesis product video on this page walks through Booster, what is in it and how to apply it, and the science video explains the stem cell released molecules behind the line.
Is SkinCrew an authorized NeoGenesis retailer in the US?
Yes. SkinCrew is an Authorized NeoGenesis US Retailer and sources every unit directly from NeoGenesis, so Booster arrives fresh, authentic and covered by the brand guarantee, with fast US shipping.

