NeoGenesis Skin Serum
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- Regular price
- $37.50
- Sale price
- $37.50
- Regular price
Skin Serum brings patented S2RM technology, stem cell released molecules from human fibroblast and adipose mesenchymal stem cells, into a lightweight formula made for every day.
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Description
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How to use
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Ingredients
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Frequently Asked Questions
Description
What is NeoGenesis Skin Serum?
NeoGenesis Skin Serum is the everyday NeoGenesis serum, built on patented S2RM technology at 20%. NeoGenesis describes it as a daily essential for correction or maintenance: it hydrates, supports the skin's natural renewal and calms the look of redness, with glycerin and propanediol to reinforce the barrier and gluconolactone, a gentle PHA, to soothe visible irritation. Dermatologist recommended and made for all skin types, it goes on damp skin after cleansing, morning and evening, and the 120 mL size is made for the chest, back, hands and arms. Available at SkinCrew in 15 mL ($82.50), 30 mL ($149.50) and 120 mL ($538.50), plus a 5 mL trial size ($37.50).
Sourced direct from NeoGenesis: guaranteed authentic, batch-fresh, fast US shipping.
The problem
Younger skin, dry or sensitive skin and skin with early signs of aging do not need the most aggressive serum on the shelf, but they do need consistent daily support, and most routines skip it. The gap shows up as dullness, dry redness-prone patches and the first fine lines, and it shows up on the chest, hands and arms long before anyone treats those areas.
The daily S2RM essential, for face and body.
Skin Serum puts the complete secretome into a daily, comfortable concentration. Growth factors and matrix-supporting proteins help improve the appearance of firmness and smooth the look of lines, humectants hydrate and reinforce the skin's protective barrier, and the PHA keeps reactive skin calm. It is the serum NeoGenesis recommends for younger skin, dry or sensitive skin, dry redness-prone skin and dry blemish-prone skin, and it is sized so larger areas can get the same comprehensive support as the face.
Key Benefits
How to use
Ingredients
Frequently Asked Questions
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NeoGenesis Skin Serum: 20% S2RM, the daily essential for face and body
NeoGenesis Skin Serum brings patented S2RM technology, stem cell released molecules from human fibroblast and adipose mesenchymal stem cells, into a lightweight formula made for every day. At 20% it is the gentlest concentration in the NeoGenesis serum family, and NeoGenesis calls it the daily essential for correction or maintenance: it hydrates, supports the skin's natural renewal and calms the look of redness, with growth factors and matrix-supporting proteins working alongside humectants and a gentle PHA.
It is the serum NeoGenesis recommends for younger skin, early signs of aging, dry or sensitive skin, dry redness-prone skin and dry blemish-prone skin. Because it comes in sizes up to 120 mL, it is also the practical choice for larger surfaces such as the chest, back, hands and arms. Dermatologist recommended and made for all skin types, it goes on damp skin after cleansing, morning and evening, under moisturizer and sunscreen. Available at SkinCrew, an Authorized NeoGenesis US Retailer, with fast US shipping.
🛡️ Authorized NeoGenesis US Retailer Guarantee
NeoGenesis sells through licensed skincare professionals and authorized retailers. SkinCrew sources every unit directly from NeoGenesis, so you receive:
Why Skin Serum Stands Out
- The S2RM secretome. Stem cell released molecules from fibroblast and adipose mesenchymal stem cells, including exosomes, ectosomes and the soluble fraction, support the skin's natural renewal process.
- Firmness and lines. Growth factors and matrix-supporting proteins help improve the appearance of skin firmness and smooth the look of lines and wrinkles.
- Humectant hydration. Glycerin and propanediol draw in water and help reduce transepidermal water loss, supporting a comfortable, resilient barrier.
- A gentle PHA. Gluconolactone refines and soothes the skin, brings antioxidant properties and helps calm visible irritation in sensitive or compromised skin.
| Feature | Skin Serum | Single growth factor serums | Hydrating serums |
|---|---|---|---|
| Active technology | Patented S2RM at 20%, the complete secretome from two stem cell sources | One growth factor or a narrow blend | Hydrators only, no growth factor content |
| Best for | Early aging, sensitive and redness-prone skin, daily maintenance, body | Usually firmness in mature skin | Basic hydration |
| Sizes | 5 mL to 120 mL, practical for face and larger areas | Typically 30 mL face only | Varies |
| Routine fit | Damp skin after cleansing, AM and PM, layers under other serums | Once or twice daily | Once or twice daily |
| How to buy | Authorized retailers only, such as SkinCrew | Varies | Mass retail |
The Skin Serum Profile
What Skin Serum Does
Benefit statements describe the appearance and feel of skin and reflect NeoGenesis product information. Individual results vary.
Who Skin Serum Is For
✅ A strong match for
- Younger skin and early signs of aging
- Dry or sensitive skin, including dry redness-prone skin
- Dry, blemish-prone skin
- Anyone who wants S2RM support on larger areas of the body
💡 Tolerance and skin type
Made for all skin types and frequently recommended by skincare professionals for dry, sensitive skin. It is fragrance free, retinoid free and built around humectants and a gentle PHA, so it can be used morning and evening from the first day.
How to Use Skin Serum
Skin Serum Ingredient Deep Dive
Human Stem Cell Conditioned Media
The fresh secretome from human fibroblast and adipose mesenchymal stem cells: released molecules from exosomes, ectosomes and the soluble fraction that help skin return to a more balanced, youthful-looking state. This is the S2RM technology, at 20% in Skin Serum.
Glycerin and Propanediol
Powerful humectants that hydrate the skin, help reduce transepidermal water loss (TEWL) and support the skin's barrier function for resilient, comfortable skin.
Gluconolactone
A gentle polyhydroxy acid (PHA) that helps refine and soothe the skin while supporting formula stability. Known for its antioxidant properties, it helps calm visible irritation and supports sensitive or compromised skin.
Full ingredient list. Water, Human Adipose Mesenchymal Stem Cell Conditioned Media, Human Fibroblast Conditioned Media, Propanediol, Glycerin, Potassium Citrate, Gluconolactone, Xanthan Gum, Sodium Benzoate, Glyceryl Polyacrylate, Chinese Senna (Cassia Obtusifolia) Seed Extract.
Watch: Skin Serum Explained
NeoGenesis made this short product video for Skin Serum, so you can see the texture, the application and where it fits in a routine before you buy.
Real Results with Skin Serum
NeoGenesis publishes before and after photos from its professional partners. These cases used Skin Serum as part of a NeoGenesis routine, and each caption lists every product involved.
Dark spots and uneven tone. Products used: Skin Serum, Intensive Moisturizer.
Photos courtesy of Pamela Vendetti, Pamela V Skincare. Individual results vary.
Visible signs of aging, eye area. Products used: Skin Serum, Intensive Moisturizer.
Photos courtesy of NeoGenesis. Individual results vary.Within 48 hours I could feel a real difference in the texture of my skin; it felt so soft and hydrated.Shared by NeoGenesis
Stubborn dark spots. Products used: Skin Serum, Vibrant C Serum, Recovery, Mandelic Acid 8% and more.
Photos courtesy of Tara Farrar, Emerald Studio for Permanent Makeup. Individual results vary.
Crepey skin. Products used: Recovery, Skin Serum.
Photos courtesy of Donna Glazer, Face It Skin Clinic. Individual results vary.Photos courtesy of NeoGenesis professional partners. Unretouched photos supplied by the brand. Individual results vary.
The Science Behind S2RM
S2RM stands for stem cell released molecules. NeoGenesis describes it as the complete secretome of human fibroblast and adipose mesenchymal stem cells: the growth factors, peptides, cytokines, antioxidants and extracellular vesicles, including exosomes, that these cells naturally release. The products contain conditioned media, the molecules the cells secrete, and no live cells.
The brand names Dr. Raja Sivamani, a dermatologist, as Head of its Scientific Medical Advisory Board, and describes its products as dermatologist recommended. NeoGenesis states that S2RM is patented and that the technology is made for all skin types.
NeoGenesis also publishes research on its product pages under titles such as the ones below. We quote these as brand statements rather than as SkinCrew claims.
- Systems Therapeutics Approach
- Rescue of Degenerating Cells Using S2RM
- Safety Profile of S2RM Technology
Watch: Understanding the S2RM secretome
How to Use Skin Serum in a NeoGenesis Routine
After cleansing, apply Skin Serum to damp skin, on the face or on larger areas such as the chest, back, hands and arms. Use morning and evening for consistent results.
Step 1: Cleanse
Step 2: Treat
Step 3: Moisturize and Protect
Pairs Well With Skin Serum
NeoGenesis builds its routine in layers: cleanse, S2RM serum, targeted step, moisturizer. These are the products the brand pairs with Skin Serum.
Browse the full range in the NeoGenesis collection, or shop by concern in Sensitive skin, Dry skin, Normal skin.
Shop Related Skincare
The brand, category and concern pages this product belongs to at SkinCrew.
Read the Guides
Side-by-side comparisons and brand guides from The Skin Edit.
Not Sure Where Skin Serum Fits in Your Routine?
A SkinCrew skincare expert can tell you which NeoGenesis S2RM concentration suits your skin, how to layer Skin Serum with the S2RM serums and what you already use, and what to expect in the first weeks. Consultations are complimentary and we are an Authorized NeoGenesis US Retailer.
Contact Our Skincare ExpertsNeoGenesis Skin Serum is a cosmetic product. NeoGenesis S2RM products contain conditioned media, the molecules released by cells, and no live cells. Statements on this page describe the appearance of skin and reflect NeoGenesis product information. Individual results vary.
NeoGenesis Skin Serum FAQ
What is NeoGenesis Skin Serum?
Skin Serum is the everyday NeoGenesis serum, featuring patented S2RM technology at 20%. S2RM means stem cell released molecules, the complete secretome from human fibroblast and adipose mesenchymal stem cells. NeoGenesis describes it as a daily essential for correction or maintenance: it hydrates, supports the skin's natural renewal and calms the look of redness in a lightweight, versatile formula.
How do I use Skin Serum?
After cleansing, apply Skin Serum to damp skin. Follow with any additional serums, then immediately apply moisturizer and/or sunscreen. Use it morning and evening. It comes in 5 mL, 15 mL, 30 mL and 120 mL, and the larger size is meant for areas like the chest, back, hands and arms.
Who is Skin Serum best for?
NeoGenesis recommends Skin Serum for younger skin, early signs of aging, dry or sensitive skin, dry redness-prone skin and dry blemish-prone skin. It is also the brand's pick for larger areas of the body where maintaining skin quality is a priority. It is dermatologist recommended and made for all skin types.
How is Skin Serum different from Recovery and Booster?
They share the same S2RM technology at different concentrations. Recovery is 70%, the highest potency, for correction and for skin that is stressed or compromised. Booster is 40% with a bioavailable hyaluronic acid and amino acids, for dryness, fine lines and firmness. Skin Serum is 20%, the lightest option, made for daily maintenance, early signs of aging, sensitive skin and the body.
Is Skin Serum good for preventative aging?
Yes. NeoGenesis positions it as the serum for maintaining skin before deeper lines and more advanced changes develop. It supports the skin's natural renewal process while improving the appearance of early fine lines, uneven texture, visible redness and overall skin quality, which makes it a sensible long-term daily serum.
How long until I see results?
NeoGenesis does not publish a fixed timeline for Skin Serum. The brand's guidance is consistent use, morning and evening, because the benefits to early signs of aging, uneven texture and visible redness build with daily application. Hydration and comfort are the first things most people notice.
Can I use Skin Serum with retinoids, vitamin C or exfoliating acids?
Yes. NeoGenesis designs its targeted products, including Skin Restore Serum (vitamin A), Vibrant C Serum, Salicylic Acid Gel and Mandelic Acid 8%, to be applied after an S2RM serum. Apply Skin Serum to damp skin first, layer the active over it, then finish with moisturizer and/or sunscreen. Use sunscreen daily when exfoliating acids are in the routine.
Are there before and after photos for Skin Serum?
Yes. NeoGenesis publishes before and after case photos from its professional partners, and a selection that used Skin Serum is shown on this page with every product in the routine listed in the caption. Individual results vary.
Is there a video on how to use Skin Serum?
Yes. The NeoGenesis product video on this page walks through Skin Serum, what is in it and how to apply it, and the science video explains the stem cell released molecules behind the line.
Is SkinCrew an authorized NeoGenesis retailer in the US?
Yes. SkinCrew is an Authorized NeoGenesis US Retailer and sources every unit directly from NeoGenesis, so Skin Serum arrives fresh, authentic and covered by the brand guarantee, with fast US shipping.