Collection: Plated Skin Science

( plated )™ is a regenerative skincare line built on Human Platelet Extract (HPE) exosome technology, developed by Rion Aesthetics from research originating at Mayo Clinic. Exosomes are tiny extracellular vesicles that carry growth factors and signaling molecules, helping support the skin and scalp's own renewal processes. It is one of the few skincare lines with published, peer-reviewed clinical studies on the actual finished products.

Yes. The ( plated )™ Intense / Intensive Repair Serum was studied in the Aesthetic Surgery Journal (2022), showing statistically significant improvements in redness, wrinkles, brown spots, luminosity, and color evenness over 6 weeks. The ( plated )™ Hair Serum was studied in a double-blind, placebo-controlled trial published in Plastic and Reconstructive Surgery Global Open (2025), showing significant improvements in hair density, fullness, and scalp coverage. Full citations are listed on this page.

Exosomes are extracellular vesicles, roughly 40 to 250 nanometers in size, that act as messengers for cell-to-cell communication. They carry proteins and nucleic acids that, in skin, are linked to renewal, wound healing, and barrier support. ( plated )™ uses platelet-derived exosomes from Human Platelet Extract.

The Intense Serum is the maximum-strength formula, studied for overall skin rejuvenation, and is the line's hero product. The Daily Serum is an everyday, defense-oriented serum studied as a cosmetic product for reducing facial redness. Many people use Intense as their primary treatment and Daily for ongoing maintenance.

In a double-blind, placebo-controlled study of 39 participants published in 2025, the ( plated )™ Hair Serum produced statistically significant improvements over placebo in hair density, scalp coverage, and volume/fullness, with measured increases in hair count of up to 13.1% and no adverse events. As with all cosmetics, individual results vary. Our specialists can help set expectations for your situation.

Across the published studies, ( plated )™ serums were reported as safe and well-tolerated, with no significant adverse events; the most commonly noted effect was mild dryness in the skin study, partly attributed to winter conditions. Because it works by supporting natural signaling rather than aggressive exfoliation, it is often suitable for sensitive skin, though anyone can patch test or consult first.

Most ( plated )™ serums are applied to clean skin (or scalp, for the Hair Serum), typically once or twice daily, followed by moisturizer and, in the morning, SPF. The studies used the serums within a simple, gentle routine. Our specialists can build a complete ( plated )™ routine for your skin.

Both are carried by SkinCrew and serve different needs. AlumierMD is a medical-grade line built on classic actives like retinol and vitamin C, while ( plated )™ is an exosome-based regenerative line with published clinical studies on its finished serums. Many clients use ( plated )™ for regeneration and tolerability alongside AlumierMD actives. Our specialists can help you combine them.

Both are available at SkinCrew. Vivier is a pharmaceutical-grade line known for its patented GrenzCine and vitamin C technology, while ( plated )™ is built on platelet-derived exosomes with peer-reviewed studies on the actual products. They take different scientific approaches to aging and can complement each other in a routine.

Both are professional lines carried by SkinCrew. SkinCeuticals is best known for antioxidant vitamin C serums like C E Ferulic, while ( plated )™ is an exosome regenerative platform with clinical studies on its skin and hair serums. The best choice depends on whether your priority is antioxidant defense or regenerative signaling — our team can help.

Yes. SkinCrew is an authorized US retailer of ( plated )™ Skin Science, so every serum is genuine, fresh, and stored correctly, backed by the full manufacturer guarantee. Exosome products are sensitive, so buying from an authorized retailer protects their integrity.

Marketplaces often carry expired, counterfeit, or heat-damaged product from unauthorized sellers, and exosome-based serums are especially sensitive to mishandling. Buying from an authorized retailer like SkinCrew guarantees fresh, authentic product with full brand backing and up to 20% cashback.