SkinCeuticals P-TIOX
- Regular price
- $150.00
- Sale price
- $150.00
- Regular price
SkinCeuticals P-TIOX is a peptide-powered corrective serum with an advanced peptide complex, 5% PHA, 5% niacinamide and 1% laminaria extract that visibly reduces 9 types of contraction lines and reveals smooth, radiant skin.
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Description
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Key Benefits
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How to use
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Ingredients
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Frequently Asked Questions
Description
What is SkinCeuticals P-TIOX?
SkinCeuticals P-TIOX is a peptide-powered anti-wrinkle serum inspired by the effects of neurotoxin injections. It combines an advanced peptide complex of 2% hexapeptide and 2% dipeptide with 5% PHA, 5% niacinamide and 1% laminaria extract to visibly reduce 9 types of contraction lines and reveal what SkinCeuticals calls glass skin radiance in 1 week. It is physician-tested to complement neurotoxin injections and also works on its own, and it suits all skin types and tones. Apply 5 to 6 drops twice daily after an antioxidant serum, then follow with moisturizer and, in the morning, sunscreen. Available at SkinCrew in 30 ml ($150).
Sourced direct from SkinCeuticals: guaranteed authentic, batch-fresh, fast US shipping.
The problem
Expression lines form where the face moves most: across the forehead, between the brows, around the eyes and mouth. Most serums hydrate or brighten but do little for the look of these lines, and injectables only reach certain areas and fade between appointments. Meanwhile skin can still look dull and uneven in texture, even when the lines themselves have been softened.
A serum built around the lines that movement makes.
P-TIOX pairs two peptides chosen for contraction lines with ingredients that work on the skin surface. Polyhydroxy acid gently exfoliates while holding water, niacinamide supports the moisture barrier for smoothness and radiance, and laminaria extract rounds out the formula. SkinCeuticals reports a visible reduction in 9 types of contraction lines, including areas that are hard to address with injections.
Key Benefits
How to use
Ingredients
Frequently Asked Questions
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SkinCeuticals P-TIOX: a peptide serum for expression lines and glass skin radiance
SkinCeuticals P-TIOX is the brand's peptide serum for wrinkle modulation, developed with the effects of neurotoxin injections in mind. Its advanced peptide complex combines 2% hexapeptide and 2% dipeptide, and SkinCeuticals reports that the formula visibly reduces 9 types of contraction lines, from forehead lines and crow's feet to nasolabial folds and marionette lines, with consistent twice-daily use.
The peptides are amplified by 5% PHA, a gentle exfoliant with humectant properties, 5% niacinamide and 1% laminaria extract, which together smooth texture and bring out radiance. SkinCeuticals describes P-TIOX as fragrance-free, paraben-free, dye-free and silicone-free, physician-tested to complement neurotoxin injections, and suitable for all skin types and tones. Available at SkinCrew, an Authorized SkinCeuticals US Retailer, with fast US shipping.
Authorized SkinCeuticals US Retailer Guarantee
SkinCeuticals is a professional skincare brand sold through dermatologists, plastic surgeons, medical spas and authorized retailers. SkinCrew sources every unit directly from SkinCeuticals, so you receive:
Why P-TIOX Stands Out
- Two peptides, one target. A 2% hexapeptide and a 2% dipeptide make up the advanced peptide complex, which SkinCeuticals designed around the mechanism that inspired it: the look of lines caused by repeated facial contraction.
- Nine types of contraction lines. SkinCeuticals reports a visible reduction in 9 types of lines, including areas that are hard to address with neurotoxin injections.
- Radiance in 1 week. 5% PHA and 5% niacinamide refine texture and tone at the surface, and SkinCeuticals states the serum reveals glass skin radiance in 1 week.
- With or without injectables. P-TIOX is physician-tested to complement neurotoxin injections, and SkinCeuticals also positions it for people who want advanced results without professional injectables.
| Feature | P-TIOX | Typical peptide serums | Hydrating serums |
|---|---|---|---|
| Main focus | Expression lines plus surface radiance | General firmness or hydration | Moisture and plumpness |
| Peptides | 2% hexapeptide and 2% dipeptide | Often undisclosed levels | Usually none |
| Exfoliation | 5% PHA, gentle and humectant | Usually none | None |
| Barrier support | 5% niacinamide | Varies | Humectants only |
| Use with injectables | Physician-tested to complement them | Rarely tested | Not a stated purpose |
The P-TIOX Profile
What P-TIOX Does
Benefit statements describe the appearance and feel of skin and reflect SkinCeuticals product information. Individual results vary.
Who P-TIOX Is For
A strong match for
- Anyone bothered by forehead lines, crow's feet or lines around the mouth
- People who get neurotoxin injections and want a serum tested alongside them
- People who want smoother, more radiant skin without injectables
- All skin types and tones, including sensitive skin
Tolerance and skin type
SkinCeuticals lists P-TIOX as suitable for normal, oily, combination, dry and sensitive skin, and all skin tones. The formula contains polyhydroxy acid, so wear a broad-spectrum sunscreen every morning.
How to Use P-TIOX
P-TIOX Ingredient Deep Dive
Advanced Peptide Complex (2% Hexapeptide and 2% Dipeptide)
Two peptides inspired by the neurotoxin mechanism of action. SkinCeuticals includes them to visibly reduce contraction lines.
5% PHA (Gluconolactone)
A polyhydroxy acid: a gentle chemical exfoliant with humectant properties that improves the look of texture and tone while maintaining hydration.
5% Niacinamide
A form of vitamin B3 that strengthens the skin's moisture barrier to improve smoothness and radiance.
1% Laminaria Extract
A marine extract from brown seaweed that SkinCeuticals formulates into P-TIOX to support firm, smooth-looking skin.
Full ingredient list. Water, Niacinamide, Gluconolactone, Butylene Glycol, PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin, Alcohol Denat., Pentylene Glycol, Methyl Gluceth-20, Glycerin, Potassium Hydroxide, Hydroxyethylcellulose, Salicylic Acid, Chlorphenesin, Phytic Acid, Adenosine, Sodium Benzoate, Laminaria Digitata Extract, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetyl Hexapeptide-8. Ingredient lists can change. Refer to the product packaging for the most current list.
How to Use P-TIOX in a Daily Routine
P-TIOX is a Correct step. It goes on after your antioxidant serum, morning and night, and before moisturizer and sunscreen.
Step 1: Prevent
Step 2: Correct
Step 3: Moisturize and Protect
Pairs Well With P-TIOX
SkinCeuticals builds its P-TIOX regimen around a morning vitamin C serum, a night antioxidant and a corrective cream. These are the closest partners.
Browse the full range in the SkinCeuticals collection, or shop by concern in Peptide skincare, Fine lines and wrinkles, Serums.
Not Sure Where P-TIOX Fits in Your Routine?
A SkinCrew skincare expert can help you choose between P-TIOX, P-TIOX Cream and A.G.E. Interrupter Advanced based on your skin type and the lines you want to soften. Consultations are complimentary and we are an Authorized SkinCeuticals US Retailer.
Contact Our Skincare ExpertsSkinCeuticals P-TIOX is a cosmetic skincare product. Statements describe the appearance and feel of skin and reflect SkinCeuticals product information. It is not intended to diagnose, treat or prevent any disease. Individual results vary.
SkinCeuticals P-TIOX FAQ
What does SkinCeuticals P-TIOX do?
P-TIOX is a peptide serum that visibly reduces the look of contraction lines and improves radiance. SkinCeuticals reports a visible reduction in 9 types of contraction lines and glass skin radiance in 1 week, from a formula with an advanced peptide complex, 5% PHA, 5% niacinamide and 1% laminaria extract.
How do I use P-TIOX?
Use P-TIOX twice daily. After cleansing and applying an antioxidant serum, apply 5 to 6 drops to the face, then follow with moisturizer. In the morning, finish with a broad-spectrum sunscreen.
Can I use P-TIOX with vitamin C?
Yes. SkinCeuticals places P-TIOX directly after an antioxidant serum. Its morning regimen pairs C E Ferulic with P-TIOX, and its evening regimen pairs Resveratrol B E with P-TIOX, followed by a moisturizer.
Is P-TIOX a replacement for neurotoxin injections?
No. P-TIOX is a cosmetic serum that improves the appearance of contraction lines. SkinCeuticals describes it as physician-tested to complement neurotoxin injections, and as an option for people who want advanced results without professional injectables.
What is the difference between P-TIOX and P-TIOX Cream?
P-TIOX is the serum step and P-TIOX Cream is the moisturizer step. The serum centers on hexapeptide, dipeptide, PHA and niacinamide for all skin types. The cream adds 10% Myrixin and 2% tripeptide for deep-set wrinkles and pore visibility. SkinCeuticals designed them to be layered, serum first.
Is P-TIOX suitable for sensitive skin?
Yes. SkinCeuticals lists P-TIOX as suitable for all skin types and tones, including sensitive skin. Its exfoliant is a polyhydroxy acid, which SkinCeuticals describes as gentle and humectant, and the formula is fragrance-free and dye-free.
When will I see results from P-TIOX?
SkinCeuticals states that P-TIOX reveals glass skin radiance in 1 week. On skinceuticals.com the brand reports a reduction in the appearance of 9 expression line types at 12 weeks of twice-daily use. Individual results vary.
Is SkinCrew an authorized SkinCeuticals retailer in the US?
Yes. SkinCrew is an Authorized SkinCeuticals US Retailer and sources every unit directly from SkinCeuticals, so P-TIOX arrives fresh, authentic and in current packaging, with fast US shipping.

