SkinCeuticals A.G.E. Interrupter Advanced
- Regular price
- $185.00
- Sale price
- $185.00
- Regular price
SkinCeuticals A.G.E. Interrupter Advanced is a concentrated corrective face cream with 18% Proxylane, 4.25% wild fruit flavonoids and 0.1% glycyrrhetinic acid that improves the look of lines, wrinkles and lost firmness in mature skin.
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Description
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Description
What is SkinCeuticals A.G.E. Interrupter Advanced?
SkinCeuticals A.G.E. Interrupter Advanced is a concentrated corrective cream for visible signs of aging that SkinCeuticals links to glycation and collagen decline. It is formulated with 18% concentrated Proxylane, 4.25% wild fruit flavonoids and 0.1% glycyrrhetinic acid, alongside 3% HEPES and 1% niacinamide. SkinCeuticals reports that it smooths visible lines and wrinkles in five facial zones and delivers rich hydration with a satin finish. It suits normal, combination, dry and sensitive skin. Massage a thin, even layer onto the face, neck and chest twice daily, after a vitamin C serum and before sunscreen in the morning. Available at SkinCrew in 48 ml ($185).
Sourced direct from SkinCeuticals: guaranteed authentic, batch-fresh, fast US shipping.
The problem
Mature skin changes in ways a basic moisturizer cannot answer. Lines deepen across the forehead, between the brows and around the mouth, skin looks less dense and less firm, and tone turns dull or sallow. SkinCeuticals connects part of this to glycation, a process in which sugars bind to the proteins that keep skin looking firm and smooth.
A corrective cream aimed at glycation and visible wrinkles.
A.G.E. Interrupter Advanced draws on more than 15 years of SkinCeuticals glycation research. It combines a high 18% level of Proxylane with a blueberry and pomegranate flavonoid blend, glycyrrhetinic acid, HEPES and niacinamide in a rich cream that hydrates deeply and leaves a satin finish, and the brand reports improvement in the look of fine lines and deep wrinkles after 12 weeks.
Key Benefits
How to use
Ingredients
Frequently Asked Questions
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SkinCeuticals A.G.E. Interrupter Advanced: a concentrated cream for visible wrinkles and lost firmness
SkinCeuticals A.G.E. Interrupter Advanced is the brand's flagship corrective cream for mature skin, built on 18% concentrated Proxylane. After 12 weeks in a SkinCeuticals study, the brand reports a 14% reduction in the look of global fine lines, an 11.5% reduction in forehead wrinkles and an 11% reduction in nasolabial folds, with improvement across five facial zones.
The formula is designed to help address the complete multi-phase glycation process that SkinCeuticals associates with visible aging. Wild fruit flavonoids provide antioxidant protection, glycyrrhetinic acid enhances natural radiance, HEPES supports surface renewal and niacinamide supports the skin barrier. It is free of parabens, drying alcohol and dyes. Available at SkinCrew, an Authorized SkinCeuticals US Retailer, with fast US shipping.
Authorized SkinCeuticals US Retailer Guarantee
SkinCeuticals is a professional skincare brand sold through dermatologists, plastic surgeons, medical spas and authorized retailers. SkinCrew sources every unit directly from SkinCeuticals, so you receive:
Why A.G.E. Interrupter Advanced Stands Out
- 18% Proxylane. One of the highest Proxylane concentrations in the SkinCeuticals range, included to improve the look of wrinkles and laxity.
- Formulated around glycation. SkinCeuticals backs the cream with more than 15 years of glycation research and designs it to help address the complete multi-phase glycation process.
- Five facial zones. SkinCeuticals reports improvement after 12 weeks in the look of fine lines and deep wrinkles in five key zones, including the forehead, crow's feet and nasolabial folds.
- Rich but refined. The cream delivers rich hydration with a satin finish and is free of parabens, drying alcohol and dyes.
| Feature | A.G.E. Interrupter Advanced | Typical anti-aging moisturizers | Basic rich night creams |
|---|---|---|---|
| Main purpose | Correct visible lines, wrinkles and lost firmness | Hydrate and soften fine lines | Moisture and comfort |
| Key technology | 18% Proxylane, 4.25% flavonoid blend | Varies, percentages rarely stated | Emollients and occlusives |
| Glycation focus | Yes, the formula's central target | Rarely addressed | Not addressed |
| When to use | Morning and evening | Morning or evening | Evening |
| Finish | Rich hydration, satin finish | Varies | Often heavy |
The A.G.E. Interrupter Advanced Profile
What A.G.E. Interrupter Advanced Does
Benefit statements describe the appearance and feel of skin and reflect SkinCeuticals product information. Individual results vary.
Who A.G.E. Interrupter Advanced Is For
A strong match for
- Mature skin with visible lines, wrinkles and lost firmness
- Normal, combination, dry and sensitive skin types
- People who want a corrective cream for face, neck and chest
- Anyone building a routine around aesthetic procedures, with their provider's guidance
Tolerance and skin type
SkinCeuticals recommends A.G.E. Interrupter Advanced for normal, combination, dry and sensitive skin. The cream is rich and contains fragrance, so very oily or fragrance-sensitive skin may prefer another option. Use a broad-spectrum sunscreen over it every morning.
How to Use A.G.E. Interrupter Advanced
A.G.E. Interrupter Advanced Ingredient Deep Dive
Concentrated Proxylane 18%
A molecule listed as hydroxypropyl tetrahydropyrantriol. SkinCeuticals includes it at a high level to improve the look of wrinkles and laxity.
Wild Fruit Flavonoids 4.25%
An antioxidant blend of blueberry and pomegranate extracts that helps protect against free radicals and is aimed at glycation, including UV-induced glycation.
Glycyrrhetinic Acid 0.1%
A soothing ingredient that helps enhance the skin's natural radiance to counter dull and sallow tone.
HEPES 3% and Niacinamide 1%
HEPES supports surface renewal and replenishes moisture. Niacinamide supports the skin barrier and helps improve the appearance of discoloration.
Full ingredient list. Water, Hydroxypropyl Tetrahydropyrantriol, Glycerin, Propylene Glycol, Stearic Acid, Butyrospermum Parkii Butter / Shea Butter, Hydroxyethylpiperazine Ethane Sulfonic Acid, Palmitic Acid, Pentylene Glycol, Oleyl Alcohol, Arachidyl Alcohol, Myristyl Myristate, Panthenol, Niacinamide, Dimethicone, Isononyl Isononanoate, Bis-PEG/PPG-16/16 PEG/PPG-16/16 Dimethicone, Glyceryl Stearate, Candelilla Cera / Candelilla Wax, Behenyl Alcohol, PEG-100 Stearate, Sodium Polyacrylate, Pentaerythrityl Tetraisostearate, 4-T-Butylcyclohexanol, Arachidyl Glucoside, Caprylyl Glycol, Xanthan Gum, Chlorphenesin, Myristic Acid, Caprylic/Capric Triglyceride, Glycyrrhetinic Acid, Parfum / Fragrance, Sorbitol, Vaccinium Myrtillus Fruit Extract, Potassium Hydroxide, Adenosine, Citric Acid, Punica Granatum Fruit Extract, Limonene, Coumarin, Linalool, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate. Ingredient lists can change. Refer to the product packaging for the most current list.
How to Use A.G.E. Interrupter Advanced in a Daily Routine
SkinCeuticals builds its routine for mature skin around this cream: an antioxidant first, C E Ferulic in the morning or Resveratrol B E at night, then H.A. Intensifier, then A.G.E. Interrupter Advanced, with sunscreen to finish the morning.
Step 1: Prevent
Step 2: Correct
Step 3: Protect
Pairs Well With A.G.E. Interrupter Advanced
These SkinCeuticals products are the ones the brand layers with A.G.E. Interrupter Advanced, plus the closest alternative cream for dry, aging skin.
Browse the full range in the SkinCeuticals collection, or shop by concern in Fine lines and wrinkles, Skin firming, Day and night creams.
Which SkinCeuticals Anti-Aging Cream Suits Your Skin?
A SkinCrew skincare expert can help you choose between A.G.E. Interrupter Advanced, Triple Lipid Restore 2:4:2 and Advanced RGN-6 based on your skin type and the changes you most want to address. Consultations are complimentary and we are an Authorized SkinCeuticals US Retailer.
Contact Our Skincare ExpertsSkinCeuticals A.G.E. Interrupter Advanced is a cosmetic skincare product. Statements describe the appearance and feel of skin and reflect SkinCeuticals product information. It is not intended to diagnose, treat or prevent any disease. Individual results vary.
SkinCeuticals A.G.E. Interrupter Advanced FAQ
What does SkinCeuticals A.G.E. Interrupter Advanced do?
It is a concentrated corrective cream that improves the look of lines, wrinkles and lost firmness in mature skin. SkinCeuticals formulates it with 18% Proxylane, 4.25% wild fruit flavonoids and 0.1% glycyrrhetinic acid to help correct and defend against visible signs of aging linked to glycation and collagen decline.
How do I use A.G.E. Interrupter Advanced?
Massage a thin, even layer onto the entire face, neck and chest twice daily. In the morning, apply it after a SkinCeuticals vitamin C antioxidant serum and before sunscreen. At night, if you use a retinol, SkinCeuticals directs you to apply the cream after the retinol.
What is glycation and why does it matter for skin?
Glycation is a process in which sugars bind to proteins such as collagen. SkinCeuticals associates the resulting advanced glycation end-products, or A.G.E.s, with visibly aged skin: wrinkles, lost firmness and a dull, sallow tone. A.G.E. Interrupter Advanced is designed to help address the complete multi-phase glycation process.
How long does A.G.E. Interrupter Advanced take to show results?
SkinCeuticals reports its results at 12 weeks. In the brand's study, the look of global fine lines was reduced by 14%, forehead wrinkles by 11.5% and nasolabial folds by 11%, with improvement in five key facial zones. Hydration and a smoother feel are noticeable from the first use. Individual results vary.
Can I use A.G.E. Interrupter Advanced with retinol or vitamin C?
Yes. SkinCeuticals recommends applying it after a vitamin C antioxidant serum such as C E Ferulic in the morning, and after retinol application at night. The cream acts as the moisturizing, corrective layer over those serums.
What is the difference between A.G.E. Interrupter Advanced and Triple Lipid Restore 2:4:2?
A.G.E. Interrupter Advanced is built on 18% Proxylane and flavonoids to target the look of wrinkles and firmness linked to glycation. Triple Lipid Restore 2:4:2 is a lipid-replenishing cream of ceramides, cholesterol and fatty acids for dry, aging skin. Some people use one in the morning and the other at night.
Is A.G.E. Interrupter Advanced fragrance-free?
No. The ingredient list includes fragrance. SkinCeuticals states that the cream is free of parabens, drying alcohol and dyes and lists it for normal, combination, dry and sensitive skin, but if your skin reacts to fragrance, consider a fragrance-free alternative such as Advanced RGN-6.
Is SkinCrew an authorized SkinCeuticals retailer in the US?
Yes. SkinCrew is an Authorized SkinCeuticals US Retailer and sources every unit directly from SkinCeuticals, so A.G.E. Interrupter Advanced arrives fresh, authentic and in current packaging, with fast US shipping.

