skinbetter science BioRewind™ Skin Health Dietary Supplement
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- Regular price
- $135.00
- Sale price
- $135.00
- Regular price
skinbetter science BioRewind Skin Health Dietary Supplement is a clinically tested daily capsule with CORExtract rosmarinic acid, biotin and zinc that helps reverse glycation to reduce the look of dullness, rough texture and redness.
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Description
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Frequently Asked Questions
Description
What is skinbetter science BioRewind™ Skin Health Dietary Supplement?
BioRewind is skinbetter science's first oral product: a daily capsule built on CORExtract Biotechnology, a proprietary rosemary-derived Rosmarinic Acid combined with synergistic antioxidants, plus biotin and zinc. It targets glycation, the reaction in which sugars bind to proteins and form Advanced Glycation End Products that cross-link collagen and elastin and show up on the surface as dullness, rough texture and redness. In a double-blinded, randomized, placebo-controlled trial in 52 subjects, visible improvement was recorded as early as eight weeks. One size: 60 capsules, $135. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Sourced direct through official skinbetter science channels: guaranteed authentic, batch-fresh, fast US shipping.
The problem
You can wear sunscreen daily, use a retinoid nightly and still watch your skin lose its clarity. Part of the reason is glycation: sugars in the body bind to structural proteins and form Advanced Glycation End Products, which accumulate with age and stiffen the collagen and elastin that keep skin resilient. On the surface it reads as dullness, rough texture and a persistent ruddy cast that creams do not correct.
The Skin Aging Pathway Your Topicals Never Touch
BioRewind was developed to address that pathway from the inside. CORExtract Biotechnology, a rosemary-derived Rosmarinic Acid with synergistic antioxidants, was shown to reverse glycation in clinical testing, with three supporting papers published in the Journal of Clinical and Aesthetic Dermatology in 2025. In a 52-subject, double-blinded, randomized, placebo-controlled trial, participants recorded a 26% reduction in rough skin texture and 23% reduction in skin dullness at eight weeks, improving to 30% and 28% at twelve weeks. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Key Benefits
How to use
Ingredients
Frequently Asked Questions
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skinbetter science BioRewind™ Skin Health Dietary Supplement: Skin Quality From the Inside.
skinbetter science BioRewind Skin Health Dietary Supplement is the brand's first oral product, a daily capsule developed around CORExtract Biotechnology: a proprietary rosemary-derived Rosmarinic Acid paired with synergistic antioxidants, plus biotin and zinc. It targets glycation, the process in which sugars bind to proteins and form Advanced Glycation End Products (AGEs) that stiffen collagen and elastin and show up on the surface as dullness, rough texture and redness. In a double-blinded, randomized, placebo-controlled trial in 52 subjects, visible improvements were recorded as early as eight weeks. 60 capsules, $135. Shop it fresh and authentic at SkinCrew, a Preferred Authorized skinbetter science US Retailer. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
🛡️ Authorized skinbetter science US Retailer Guarantee
skinbetter science is sold only through Authorized Physician Partners. SkinCrew operates under medical direction and sources every unit directly from skinbetter science (L’Oréal Dermatological Beauty), so you receive:
Why BioRewind Stands Out
- It works on glycation, a target topicals cannot reach. Sunscreen and retinoids address UV and cell turnover. Glycation happens throughout the dermis as sugars cross-link structural proteins, and CORExtract Biotechnology was shown to reverse glycation in clinical testing, published in the Journal of Clinical and Aesthetic Dermatology (2025).
- Three peer-reviewed papers, not one press release. The efficacy trial and two mechanism papers on glycation and oxinflammation all appeared in the Journal of Clinical and Aesthetic Dermatology in 2025, with authors including Draelos, Bucay, Watchmaker and Valacchi.
- Visible results measured on the face. The randomized, placebo-controlled trial in 52 subjects recorded a 26% reduction in rough skin texture, 23% in dullness and 12% in redness at eight weeks, improving to 30%, 28% and 14% at twelve weeks.
- A defined dosing protocol, not a vague 'take daily'. skinbetter science publishes the clinically tested schedule: a Quick Start month, a Transition month, then maintenance, so you know exactly how the studied regimen was run.
| Feature | BioRewind Supplement | Typical Collagen Powder | Topical Antioxidant Serum |
|---|---|---|---|
| Primary target | Glycation and AGE formation | Adds dietary collagen peptides | Surface and upper-layer free radicals |
| Route | Oral, systemic | Oral, systemic | Topical, applied skin only |
| Signature technology | CORExtract rosemary Rosmarinic Acid | Varies widely by brand | Vitamin C, E or Allyl PQQ |
| Published trial on the finished product | Yes, 52 subjects, placebo controlled, JCAD 2025 | Rarely | Product dependent |
| Visible endpoints measured | Redness, dullness, rough texture at 8 and 12 weeks | Often self-reported only | Product dependent |
| Role in a routine | Complements topicals, does not replace them | General wellness | Daily first line of defense |
The BioRewind Profile
Clinically Shown Results
Results based on a 12-week, single-center, double-blinded, randomized, placebo-controlled trial conducted in 52 subjects. Published in the Journal of Clinical and Aesthetic Dermatology, 2025 (Draelos ZD, Gueniche A, Yatskayer M, Nelson DB; 18(3):28-33), with supporting mechanism papers on glycation reversal and oxinflammation in the same journal. Unretouched clinical photography; individual results vary. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Who BioRewind Is For (and Who Should Skip It)
Reach for it if
- Your skin looks dull, rough and slightly ruddy despite a solid topical regimen, and you want to work on skin quality from another angle.
- You are in your late thirties or beyond, when the visible effects of accumulated glycation typically become noticeable.
- You want a supplement with an actual placebo-controlled trial behind it rather than a proprietary blend with no published data.
- You are willing to give it eight to twelve weeks, which is how long the study ran before recording its endpoints.
Choose something else if
- You have not yet got the basics in place; daily broad spectrum SPF and a retinoid such as AlphaRet Overnight Cream come first.
- Your main concern is discoloration or dark marks; a topical corrector like Even Tone Correcting Serum is the direct route.
- You are pregnant, nursing, taking medication or managing a medical condition, unless your physician has reviewed it with you.
- You want an overnight change; oral skin support is slow, cumulative and measured in months.
What to Expect: Week by Week
The timeline below follows the published study and the brand's clinically tested dosing schedule. Oral skin support builds gradually, so the meaningful checkpoints are eight and twelve weeks. Individual results vary. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Ingredient Deep Dive
How to Use BioRewind in a skinbetter science Regimen
BioRewind is taken orally and layered on top of, not instead of, your topical routine. The standard dose is 2 capsules daily with meals. The clinically tested schedule runs Quick Start in month one, Transition in month two and maintenance from month three. Pair it with the regimen below. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Daily: Take
Morning: Defend
Evening: Renew
Build the Regimen Around BioRewind
An oral supplement works best alongside a complete topical routine. These are the skinbetter science products most often paired with it.
See the complete range in the skinbetter science collection, or browse what we carry for redness and sensitivity and fine lines and wrinkles.
Wondering Whether a Skin Supplement Is Worth Adding?
Oral skin support only makes sense on top of a solid topical routine. A SkinCrew skincare expert can review what you are already using, tell you honestly whether BioRewind is the right next step, and help you time it against your other products. Reach out for a complimentary consultation.
Contact Our Skincare ExpertsThese statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your physician before use if you are pregnant, nursing, taking medication or have a medical condition. Keep out of reach of children.
skinbetter science BioRewind™ Skin Health Dietary Supplement FAQ
What does skinbetter science BioRewind Skin Health Dietary Supplement do?
BioRewind is a daily oral capsule that targets glycation, the process that forms Advanced Glycation End Products and stiffens collagen and elastin. In a 52-subject placebo-controlled trial it reduced rough skin texture by 26% and dullness by 23% at eight weeks. These statements have not been evaluated by the FDA.
How long does BioRewind take to work?
Visible results were recorded as early as eight weeks in the clinical trial, with larger improvements at twelve weeks: 30% reduction in rough skin texture, 28% in dullness and 14% in redness. Plan on a three-month commitment, taking the capsules consistently with meals, before judging whether BioRewind is working for you.
How do you take skinbetter BioRewind?
The standard dose is 2 capsules daily with meals. The clinically tested schedule is more structured: month one is Quick Start at 2 capsules three times daily, month two is Transition at 2 capsules twice daily, and from month three maintenance is 1 capsule twice daily, always with food.
What is glycation and why does it matter for skin?
Glycation is a non-enzymatic reaction in which sugars bind to proteins and produce Advanced Glycation End Products, or AGEs. AGEs accumulate with age and cross-link collagen and elastin. skinbetter science associates that process with the visible dullness, rough texture and redness that BioRewind Skin Health Dietary Supplement was formulated to address.
Is BioRewind backed by clinical studies?
Yes. Three papers appeared in the Journal of Clinical and Aesthetic Dermatology in 2025: a single-center, double-blinded, randomized, placebo-controlled trial in 52 subjects, plus mechanism papers on reversing glycation and on oxinflammation associated with glycative stress. That is unusually strong evidence for a skin supplement.
Can I take BioRewind with my skinbetter science topicals?
Yes, and that is how it is intended to be used. BioRewind Skin Health Dietary Supplement complements rather than replaces topical care. Keep using your morning antioxidant serum and broad spectrum sunscreen and your evening retinoid, and add the capsules on top. Consult your physician about interactions with other supplements or medication.
What is in BioRewind and does it contain collagen?
BioRewind contains CORExtract Biotechnology, a proprietary rosemary-derived Rosmarinic Acid with synergistic antioxidants, plus biotin and zinc. It does not rely on ingested collagen peptides. The approach is different: rather than adding collagen, it targets the glycation process associated with damage to existing collagen and elastin.
Can I take BioRewind while pregnant or breastfeeding?
Consult your physician before use if you are pregnant, nursing, taking medication or managing any medical condition. This applies to every dietary supplement, not only BioRewind. Keep the product out of reach of children. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Does BioRewind cause breakouts or side effects?
No adverse pattern is claimed on the product, and it was evaluated in a double-blinded, placebo-controlled trial of 52 subjects. Because it contains biotin, mention it to your physician before blood work, as high biotin intake can interfere with certain lab assays. Stop use and consult your physician if you notice any reaction.
Is BioRewind better than a collagen supplement?
They work differently. Collagen powders supply peptides; BioRewind Skin Health Dietary Supplement targets glycation, the process associated with damage to the collagen and elastin you already have. BioRewind's advantage is evidence: a published, placebo-controlled trial measuring redness, dullness and texture on the face at eight and twelve weeks.
How much does skinbetter BioRewind cost and is it worth it?
BioRewind Skin Health Dietary Supplement is $135 for 60 capsules, sold at skinbetter science's suggested retail price. Whether it is worth it depends on your routine: it earns its place once sunscreen, an antioxidant and a retinoid are already in daily use, and it has real placebo-controlled data behind it.
Where can I buy authentic skinbetter science BioRewind in the US?
skinbetter science is sold only through Authorized Physician Partners, never on open marketplaces. SkinCrew is a Preferred Authorized skinbetter science US Retailer operating under medical direction, sourcing directly from the brand, so every pack is in date, authentic, covered by the brand guarantee and shipped fast across the US.