Epicutis

Epicutis

Experience minimalist, science-driven skincare from Epicutis, designed to support skin barrier health and calm visible inflammation. Powered by clinically backed formulas and patented technology, Epicutis helps soothe sensitivity, boost hydration, and restore a healthy, balanced complexion.

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  • Epicutis Lipid Serum Epicutis Lipid Serum

    Epicutis Lipid Serum

    $250.00
    $250.00
    $250.00
  • Epicutis Hydrobiome Serum Epicutis Hydrobiome Serum

    Epicutis Hydrobiome Serum

    $165.00
    $165.00
    $165.00
  • Epicutis Cleansing Essentials Set Epicutis Cleansing Essentials Set

    Epicutis Cleansing Essentials Set

    $105.00
    $105.00
    $105.00
  • Epicutis Lipid Recovery Mask for Face (5 pack) Epicutis Lipid Recovery Mask for Face (5 pack)

    Epicutis Lipid Recovery Mask for Face (5 pack)

    $125.00
    $125.00
    $125.00
  • Epicutis Arctigenin Brightening Treatment Epicutis Arctigenin Brightening Treatment

    Epicutis Arctigenin Brightening Treatment

    $175.00
    $175.00
    $175.00
  • Epicutis Hydrobiome Mist Epicutis Hydrobiome Mist

    Epicutis Hydrobiome Mist

    $75.00
    $75.00
    $75.00
  • Epicutis Hyvia Crème Epicutis Hyvia Crème

    Epicutis Hyvia Crème

    $195.00
    $195.00
    $195.00
  • Epicutis Lipid Body Treatment Epicutis Lipid Body Treatment

    Epicutis Lipid Body Treatment

    $225.00
    $225.00
    $225.00
  • Epicutis Lipid Recovery Mask for Eyes (5 pack) Epicutis Lipid Recovery Mask for Eyes (5 pack)

    Epicutis Lipid Recovery Mask for Eyes (5 pack)

    $105.00
    $105.00
    $105.00
  • Epicutis Lipid Recovery Masks for Neck and Décolleté (5 pack) Epicutis Lipid Recovery Masks for Neck and Décolleté (5 pack)

    Epicutis Lipid Recovery Masks for Neck and Décolleté (5 pack)

    $140.00
    $140.00
    $140.00
  • Epicutis Luxury Skincare Set Epicutis Luxury Skincare Set

    Epicutis Luxury Skincare Set

    $395.00
    $395.00
    $395.00
  • Epicutis Oil Cleanser Epicutis Oil Cleanser

    Epicutis Oil Cleanser

    $85.00
    $85.00
    $85.00
  • Epicutis Lipid Shield Barrier Repair Sunscreen SPF 30 Epicutis Lipid Shield Barrier Repair Sunscreen SPF 30

    Epicutis Lipid Shield Barrier Repair Sunscreen SPF 30

    $90.00
    $90.00
    $90.00
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Epicutis Skincare

Welcome to the official Epicutis® collection at SkinCrew. Founded in Boulder, Colorado by a biophysicist alongside a Japanese master formulator, Epicutis is luxury clinical skincare built on a simple philosophy: treat skin health, not age. Its minimalist, fragrance-free range is powered by the patented TSC anti-inflammatory lipid and HYVIA™ chia complex to calm visible inflammation, support the skin barrier, and reveal a hydrated, balanced complexion—gentle enough for post-procedure skin.

🛡️ Authorized Epicutis Retailer Guarantee

Luxury lipid formulas are only as effective as they are fresh and authentic. Buying from SkinCrew ensures you receive:

✅ 100% Authentic & Fresh
Genuine, in-date product through authorized channels.
💸 Up to 5% Cashback
Join The Crew and earn rewards on every order.
🚚 Free US Shipping $99+
Fast, free shipping across the United States over $99.
🗓️ 45-Day Satisfaction
Backed by SkinCrew's 45-Day Satisfaction Guarantee.

Why Epicutis Stands Out

  • Treats Skin Health, Not Age: Epicutis is built on the idea that calm, healthy, well-functioning skin is the real goal—at any age.
  • Patented TSC Lipid: A proprietary anti-inflammatory lipid molecule at the heart of the line, formulated to soothe visible inflammation and support barrier repair.
  • HYVIA™ Chia Complex: An antioxidant-rich chia-derived complex that nourishes, hydrates, and helps defend against environmental stress.
  • Clean, Minimalist & Post-Procedure Friendly: EWG Verified and fragrance-free formulas designed to be gentle on sensitive and post-treatment skin.
Boulder, Colorado Patented TSC Lipid EWG Verified Fragrance-Free Post-Procedure Safe

Shop Epicutis Bestsellers

New to the brand? Start with these client favorites. Tap any product to shop and read full details.

$250Lipid Serum
Hero Serum
Lipid Serum
Best for: inflammation & barrier
The flagship. Patented TSC lipid to calm visible inflammation and support a healthy barrier.
Shop now →
$270Hyvia Crème
Rich Moisture
Hyvia Crème
Best for: dryness & nourishment
A luxurious HYVIA chia-complex crème to deeply nourish, hydrate, and comfort the skin.
Shop now →
$165Hydrobiome Serum
Microbiome Hydration
Hydrobiome Serum
Best for: dehydration & balance
A hydrating serum formulated to support the skin's microbiome for a balanced, dewy complexion.
Shop now →
$250Arctigenin Brightening Treatment
Brightening
Arctigenin Brightening Treatment
Best for: dullness & uneven tone
A targeted treatment to brighten and even the look of tone for a luminous, refreshed finish.
Shop now →
$126Lipid Shield SPF 30
Barrier SPF
Lipid Shield SPF 30
Best for: daily protection
A barrier-repair mineral sunscreen that protects while it supports skin health.
Shop now →
$115Oil Cleanser
Gentle Cleanse
Oil Cleanser
Best for: makeup & impurities
A nourishing oil cleanser that melts away makeup and impurities without stripping the barrier.
Shop now →
$96Hydrobiome Mist
Refresh
Hydrobiome Mist
Best for: on-the-go hydration
A refreshing mist to hydrate, soothe, and support the skin barrier any time of day.
Shop now →
$140Lipid Recovery Mask for Face (5pk)
Recovery Mask
Lipid Recovery Mask for Face (5pk)
Best for: stressed & post-procedure
Lipid-rich recovery masks to calm, hydrate, and comfort stressed or post-treatment skin.
Shop now →

The Epicutis Difference

Patented Lipid
TSC Technology
A proprietary anti-inflammatory lipid molecule formulated to calm visible inflammation and support barrier repair.
Antioxidant
HYVIA™ Chia Complex
A chia-derived antioxidant complex that nourishes, hydrates, and helps defend against environmental stress.
Microbiome
Hydrobiome System
Hydrating formulas designed to support the skin's natural microbiome for lasting balance and comfort.
Clean Formulation
EWG Verified & Fragrance-Free
Minimalist, clean formulas built to be gentle on sensitive, reactive, and post-procedure skin.

Epicutis vs. Other Barrier & Clinical Brands

Shoppers in the USA often cross-shop Epicutis against other barrier-repair and clinical brands like Epionce, Skinfix, and SkinCeuticals. Here's how they compare at a glance.

HOW EPICUTIS COMPARES
 EpicutisEpionceSkinfixSkinCeuticals
Core focusSkin health & inflammationBarrier & botanicalsBarrier & clean clinicalAntioxidant anti-aging
Hero techPatented TSC lipidBotanical lipid blendsLipid-peptide complexesL-ascorbic acid
PhilosophyTreat health, not ageBarrier-firstClean clinicalPrevent, protect, correct
Fragrance-freeYes—core principleLargelyYesVaries
Post-procedure focusYes—dedicated masksOften usedYesSome lines

Comparison reflects general brand positioning for informational purposes. All trademarks belong to their respective owners.

How to Build Your Epicutis Routine

A minimalist, barrier-first routine in three steps: Cleanse, Treat, and Moisturize & Protect.

Step 1: Cleanse

Oil CleanserGently melt away makeup and impurities without stripping.
Hydrobiome MistRefresh and hydrate to prep skin for treatment.

Step 2: Treat

Lipid SerumThe hero TSC lipid serum to calm and support the barrier.
Hydrobiome SerumLayer in microbiome-supporting hydration.
Arctigenin Brightening TreatmentAdd to target the look of dullness and uneven tone.

Step 3: Moisturize & Protect

Hyvia CrèmeSeal in moisture with the rich HYVIA chia crème.
Lipid Shield SPF 30Finish with barrier-repair mineral sun protection.

Explore More Epicutis

$110Lipid Recovery Mask for Eyes (5pk)
Lipid Recovery Mask for Eyes (5pk)
Shop now →
$150Lipid Recovery Mask Neck & Décolleté (5pk)
Lipid Recovery Mask Neck & Décolleté (5pk)
Shop now →
$300Lipid Body Treatment
Lipid Body Treatment
Shop now →
$105Cleansing Essentials Set
Cleansing Essentials Set
Shop now →
$550Luxury Skincare Set
Luxury Skincare Set
Shop now →
$70Luxury Set Discovery
Luxury Set Discovery
Shop now →

Epicutis Skincare: Frequently Asked Questions

What is Epicutis?

Epicutis is a luxury clinical skincare brand founded in Boulder, Colorado by a biophysicist alongside a Japanese master formulator. Built on the philosophy of treating skin health rather than age, its minimalist, fragrance-free formulas use a patented TSC lipid and HYVIA chia complex to calm inflammation and support the barrier.

Is Epicutis a good skincare brand?

Yes. Epicutis is a respected luxury clinical brand known for clean, fragrance-free, EWG Verified formulas. It focuses on barrier health and calming visible inflammation, making it popular for sensitive and post-procedure skin.

What is TSC in Epicutis products?

TSC is Epicutis's patented anti-inflammatory lipid molecule, the cornerstone of the Lipid Serum and broader range. It's formulated to soothe visible inflammation and support the skin's barrier repair processes.

What is HYVIA?

HYVIA is Epicutis's chia-derived antioxidant complex, featured in the Hyvia Crème. It nourishes and hydrates the skin while helping defend against environmental stress.

Is Epicutis good for sensitive or post-procedure skin?

Yes. Epicutis is fragrance-free, EWG Verified, and built around calming inflammation and supporting the barrier, which makes it well suited to sensitive and post-treatment skin. It even offers dedicated Lipid Recovery Masks. Always follow your provider's aftercare guidance.

Which Epicutis product should I start with?

Most people start with the Lipid Serum, the brand's hero TSC treatment. Pair it with the Oil Cleanser and Hyvia Crème, add the Hydrobiome Serum for hydration, and finish with Lipid Shield SPF 30.

Is Epicutis fragrance-free?

Yes. Fragrance-free, minimalist formulation is a core Epicutis principle, which is part of why the line is favored for reactive and post-procedure skin.

How does Epicutis compare to Epionce or SkinCeuticals?

All are clinical brands. Epicutis is distinguished by its patented TSC lipid and a 'treat skin health, not age' philosophy with a strong barrier and post-procedure focus. Epionce centers on botanical barrier care, Skinfix on clean clinical barrier formulas, and SkinCeuticals on antioxidant Vitamin C anti-aging.

Where can I buy authentic Epicutis in the USA?

You can buy 100% authentic Epicutis at SkinCrew, an authorized retailer that sells only genuine, in-date product, with free US shipping on orders over $99, up to 5% cashback, and a 45-Day Satisfaction Guarantee.

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Not Sure Which Epicutis Products Are Right for You?

Whether you're calming inflammation, repairing your barrier, brightening, or caring for post-procedure skin, our SkinCrew team will help you build the right Epicutis routine for your skin.

Get a Free Skincare Consultation