Intense, Daily and Calm are the three ( plated ) face serums, and they share a price: $258 each. They also share the same core technology, which is why shoppers mix them up. The differences are in the role, the size, the supporting ingredients and how often you apply them. Here is how to pick one.

Intense Serum vs Daily Serum vs Calm Serum: which should you choose?

How do the three compare side by side?

What do the three serums have in common?

Every ( plated ) product is built on what the brand calls Renewosome Technology: purified exosomes derived from human platelets, listed on the label as Human Platelet Extract. Exosomes are tiny vesicles that cells use to carry signals to one another. The serums contain the vesicles, not cells.

The three ingredient lists overlap heavily. Each one is a water-based serum with glycerin and pentylene glycol for hydration, Human Platelet Extract, arginine, silanetriol and hydrolyzed gelatin. Each is lightweight, absorbs quickly and is listed by the brand as suitable for all skin types, including sensitive skin.

So the choice is about concentration, supporting ingredients and how often you apply it, not about a different core active. If you want the science background first, read What Is Exosome Skincare?.

Who should choose Intense Serum?

( plated ) Intense Serum is the corrective one. The brand describes it as delivering a high concentration of purified exosomes and aims it at the look of fine lines, wrinkles, redness and brown spots, with visible improvement in as little as six weeks of daily use according to ( plated ). Alongside the exosomes, the formula includes panthenol and hyaluronic acid.

Choose Intense if you are starting the line with a specific concern you can see in the mirror, or if you have been told to use it by the professional who treats your skin. It is used once daily on clean, dry skin, before any other product, and left to dry completely.

When the bottle runs out, the Intense Serum Refill is a 15 mL cartridge of the same formula for $244 that fits the bottle you already have.

Who should choose Daily Serum?

( plated ) Daily Serum is the long-term one. It combines the platelet-derived exosomes with antioxidants and what the brand calls a growth factor-rich complex, adds hydration, and includes oat kernel extract. It targets the same visible concerns as Intense, the look of fine lines, redness and brown spots, with the goal of keeping skin looking even and resilient over time.

Choose Daily if you have finished a course of Intense and want to maintain how your skin looks, or if you would rather start with a serum made for steady everyday use. At 30 mL for $258 it costs half as much per mL as Intense, which matters for a product you plan to use indefinitely.

Who should choose Calm Serum?

( plated ) Calm Serum is the comfort one. It adds beta-glucan and oat kernel extract to the exosomes, gives a cooling sensation as it goes on, and is described as non-occlusive. The brand positions it to support skin before and after cosmetic procedures, and for any time skin feels stressed, sensitized or reactive, to reduce the look of redness and the feeling of discomfort.

Choose Calm if your skin is visibly red or uncomfortable after a professional treatment, or if reactivity is your main issue. It is the only one of the three with directions for repeat use: a thin layer on the affected area up to 2 to 3 times daily. After any procedure, follow the aftercare instructions from your provider first.

Can you use Intense, Daily and Calm together?

The brand describes Intense and Daily as a sequence, not a pair. Its guidance is to use Intense for 6 to 12 weeks of corrective care, then move to Daily for long-term maintenance. Both are once-daily serums that go on first, so most people use one at a time.

Calm sits outside that sequence. It is the serum to bring in around treatments or during a reactive spell, then set aside when skin feels settled. The published directions do not describe layering Calm with Intense or Daily, so the simple approach is to apply them at different times of day and let each one dry completely. If you want a plan for your situation, ask the professional who treats your skin or our clinical team.

The step-by-step version is in How to Build a ( plated ) Skin Science Routine.

How do you decide in under a minute?

Beyond the face, the same technology comes in Eye Serum ($138) for the eye contour, Body Serum ($338) for the chest, arms and hands, and Hair Serum ($379) for the scalp. All seven are ranked in The Best ( plated ) Skin Science Products. If you are comparing the category, Exosomes vs Growth Factors covers how ( plated ) differs from growth factor serums.

Where should you buy ( plated ) Skin Science?

( plated ) Skin Science is a professional skincare line, sold through skincare professionals and authorized retailers. Stock from an unauthorized seller has an unknown history and no retailer standing behind it, which matters when a single 15 mL serum costs $258.

SkinCrew is an Authorized ( plated ) Skin Science US Retailer. Every product is sourced direct through official ( plated ) Skin Science channels, arrives batch-fresh with fast US shipping, and is backed by our 45-Day Satisfaction Guarantee. Free US shipping applies to orders of $99 or more, which covers every product in the range. Shop all seven on the ( plated ) Skin Science brand page, or browse more guides on The Skin Edit.

How to check a seller is covered in Where to Buy ( plated ) Skin Science Online.

What else do people ask about the ( plated ) serums?

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